Search Results - hepatitis+c+virus+(hcv)

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Hepatitis C virus E1E2 genes stimulating development of broadly neutralizing antibodies

Unmet Need185 million people worldwide are infected with Hepatitis C (HCV). It is a major cause of liver failure and hepatocellular carcinoma. Recent development of potent, oral, interferon-free therapies have improved treatment of HCV significantly, but treatment alone is unlikely to eradicate the disease. There remain the issues of therapy being costly,...

Published: 6/27/2024 | Inventor(s): Justin Bailey, James Crowe, Andrew Flyak, George Shaw, Stuart Ray

Keywords(s): Biologics, Disease Indication, Hepatitis C Virus, Hepatitis C Virus (HCV), Infectious Diseases, Therapeutic Matter, Therapeutic Substance, Therapeutics, Vaccine, Viral Infections

Category(s): Clinical and Disease Specializations, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases > Hepatitis C Virus, Clinical and Disease Specializations > Infectious Diseases > Viral Infections

Genotype 1 HCV Pseudoparticle Library

C11773: Library of Genotype 1 Hepatitis C Virus particlesNovelty: This technology consists of a wide range of human genotype 1 hepatitis C viral (HCV-1) particles, which can be used for research and development of anti-HCV-1 therapies.Value Proposition: Availability of a library of HCV-1 viral particles provides a valuable resource for anti-HCV-1 drug...

Published: 6/27/2024 | Inventor(s): Stuart Ray, William Osburn

Keywords(s): Computing; Calculating; Counting, Data Processing Systems or Methods, Specifically Adapted fo~, Data Processing Systems or Methods, Specifically Adapted for, Disease Indication, Hepatitis C Virus (HCV), Infectious Diseases, Physics

Category(s): Technology Classifications > Computers, Electronics & Software > Financial Tech, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Infectious Diseases > Hepatitis C Virus (HCV)

A computational approach for generating representative hepatitis C virus genomic sequences

C11517: Novel Synthetic Genomic Reconstruct for HCV TherapeuticsNovelty: This technology is an optimized synthetic reconstruct of genotype 1a hepatitis C virus (HCV) that is representative of globally-circulating strains of HCVValue Proposition: The reconstructed HCV genotype 1a virus is highly functional without adaptive mutations, which allows it...

Published: 6/27/2024 | Inventor(s): Supriya Munshaw, Lin Liu, Stuart Ray

Keywords(s): Computational Modeling Tool, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Discovery/Research Tools, Disease Indication, Hepatitis C Virus (HCV), In Silico Research Tool, Infectious Diseases, Physics

Category(s): Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Infectious Diseases > Hepatitis C Virus (HCV), Technology Classifications > Research Tools

Use of Consensus Sequence as Vaccine Antigen to Enhance Recognition of Virulent Viral Variants

C04630: Use of Consensus Sequence as Vaccine Antigen to Enhance Recognition of Virulent Viral Variants Technical Details: Vaccines for diverse viruses will be most effective when they direct the recipient?s response to recognize the most virulent form of the organism. Scientists at JHU have found that circulating strains of hepatitis C virus (HCV)...

Published: 6/27/2024 | Inventor(s): Andrea Lynn Cox, David Thomas, Stuart Ray

Keywords(s): Biologics, Disease Indication, Hepatitis C Virus, Hepatitis C Virus (HCV), Infectious Diseases, Therapeutic Matter, Therapeutic Substance, Therapeutics, Vaccine, Viral Infections

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Hepatitis C Virus, Clinical and Disease Specializations > Infectious Diseases > Viral Infections, Technology Classifications > Research Tools > Nucleic Acids, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools, Technology Classifications > Therapeutic Modalities