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Apparatus and Method for modular ultrasound and photoacoustic imaging and interactive guidance using a position-tracked modular imaging framework

Value Proposition· Wearable ultrasound system that is adaptable to different patient physiologies and ages.· Allows for longitudinal and non-invasive monitoring of internal organs of critical care patients.· Applicable across a broad range of organ systems and disease indications.· Simulation-aided interactive guidance simplifies...

Published: 3/14/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Ananya Tandri

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Imaging

A novel flexible implantable electroceutical device for recording and stimulating gastric activity

Unmet Need· Gastroparesis and functional dyspepsia (FD) are debilitating stomach disorders that together affect more than 10% of the world population. · Current approaches to treatment focus on symptom management, with pharmacological treatment being first-line; treatment efficacy is limited.· Gastric electric stimulation devices...

Published: 3/14/2025 | Inventor(s): Vivek Ganesh, Martin Stebbing, Pedro Irazoqui

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Therapeutic Devices

Artifact Control and Miniaturization of the Safe DC Stimulator for Neural Prostheses

Safe DC Stimulator for Neural ProsthesesJHU Ref #: [C11822] Unmet NeedCurrently, neural prostheses are limited because they excite neurons but cannot efficiently inhibit them. Direct current (DC) can excite, inhibit, or control extracellular potential of target neurons, but DC stimulation is biologically unsafe. The current solution is to direct DC...

Published: 3/13/2025 | Inventor(s): Charles Della Santina, Gene Fridman

Keywords(s): CNS and Neurological Disorders, Disease Indication, Neuroprosthetic Sensing Algorithms, Neuroprosthetics, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Prosthetics, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices

Machine Learning Optimization for a Neural Implant

Unmet NeedElectrical stimulation with neural implants plays a crucial role in restoring sensory and motor function, as well as treating neurological disorders, including Parkinson’s disease[i], seizures, and even psychiatric disorders. Despite decades of research and development, neural implants only result in limited restoration of function in patients...

Published: 3/14/2025 | Inventor(s): Gene Fridman, Cynthia Steinhardt

Keywords(s):

Category(s): Copyright, Technology Classifications > Medical Devices > Neurostimulation

Closed-loop Peripheral Nerve Stimulation for Restoration in Chronic Pain

Unmet NeedChronic pain affects about 100-million adults in the United States and is primarily treated with drugs, which can have significant negative side effects (NIH-Institute of Medicine). A promising alternative therapy is electrical peripheral nerve stimulation (PNS) therapy. However, PNS therapy has been associated with suboptimal efficacy because...

Published: 3/14/2025 | Inventor(s): Sridevi Sarma, Christine Beauchene, Yun Guan, Claire Zurn

Keywords(s):

Category(s): Clinical and Disease Specializations > Pain > Chronic Pain, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Therapeutic Devices

Neural Stimulation Alters Native Sensory Perception

Unmet NeedElectrical stimulation to the brain is a new emerging field of research with great potential. As neurons within the brain communicate through electrical charges, the ability to manipulate the delivery of such electrical charges through a stimulation machine may be beneficial for neuro-rehabilitation. Examples of such efforts already underway...

Published: 3/14/2025 | Inventor(s): Pablo Celnik, Gabriela Cantarero, Ambarish Pawar, David McMullen, Robert Chmielewski, Margaret Thompson, Francesco Tenore, Breanne Christie, Luke Osborn, Matthew Fifer

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Neurostimulation, Clinical and Disease Specializations > Neurology

Safe Direct Current Stimulator Design for Reduced Power and Increased Reliability

Unmet NeedNeuroprostheses, such as cochlear implants and neural pacemakers, have already been proven to be useful in varying applications. Current neuroprostheses tools typically employ biphasic pulsatile stimulation, a process where electrodes have both a cathodic phase and an anodic phase to pass charge in both directions. Direct current (DC) has...

Published: 3/13/2025 | Inventor(s): Gene Fridman

Keywords(s): CNS and Neurological Disorders, Computer and Network Systems, Computer Hardware, Disease Indication, Implanted Device, Implants, Neuromodulator, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices

Nerve-sparing Surgical Guidance Using Neuromodulation-based Nerve Localization

Unmet NeedGlobally, prostate cancer is the second leading cause of cancer and the sixth leading cause of cancer-related death in men. In the U.S., prostate cancer is the most common and diagnosed cancer in males. It is estimated there are 2.5 million men living with prostate cancer in the US, and the number is on the rise. The survival of prostate...

Published: 3/14/2025 | Inventor(s): Emad Boctor, Jeeun Kang, Arthur Burnett, Jin Kang, Maged Harraz

Keywords(s): Disease Indication, Erectile Dysfunction (ED), Imaging and Sensing Systems, Imaging Modality, Implanted Device, Implants, In Vivo Medical Imaging, Integrated Imaging System, Integrated Robotic and Imaging System, Interventional and Surgical Systems, Men's Health, Neuromodulator, Surgical Navigation, Therapeutic Devices, Therapeutics, Ultrasound (US)

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Men's Health

Initial Proof-of-Concept of Photoacoustic Neural Stimulation; A Potential Approach to Retinal Stimulation: Preliminary In Vitro Study

Unmet NeedNon-cataract related vision loss affects 22.9 million people worldwide. Many of these patients retain partial functionality in their retinas; even though their outer retinas no longer function, visual stimulation can be achieved by sending messages from the inner retinas through the optic nerves. Present efforts to restore vision to these...

Published: 3/13/2025 | Inventor(s): Emad Boctor, James Spicer, Peter Gehlbach, Jeeun Kang, Maged Harraz

Keywords(s): Disease Indication, Environmental Sensing, Eye Disorders, Imaging and Sensing Systems, Implanted Device, Implants, Neuromodulator, Photodetector, Sensors, Signal Display Software, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Computers, Electronics & Software > Sensors, Technology Classifications > Industrial Tech > Energy, Infrastructure & Environment, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Industrial Tech, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices > Neurostimulation

System and Method for Phase Dependent Brain Neuromodulation

Unmet Need Neuromodulation is a technology that involves the spatiotemporal alteration of brain activity with electrical, magnetic, or chemical stimulation. Neuromodulation devices can be implantable or non-implantable and target specific areas of the body in order to restore proper activity to a malfunctioning nervous system most commonly...

Published: 3/13/2025 | Inventor(s): William Anderson, Yousef Salimpour, Leon Chen, Kelly Mills

Keywords(s): Brain Stimulation, CNS and Neurological Disorders, Disease Indication, Implanted Device, Implants, Interventional and Surgical Systems, Neuromodulator, Surgical Intervention Method, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices

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