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NKCC1-pcDNA3-GFP
Invention novelty: This tangible material is a plasmid vector expressing a NKCC1-EGFP fusion protein. Value Proposition: NKCC1 (Na+-K+-Cl- cotransporter 1) regulates cell volume and accumulation of intracellular Cl- and has been shown to promote invasiveness of brain tumor cells by modulating cell adhesion and cell migration. This vector is a tool that...
Published: 3/13/2025
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Inventor(s):
Tomas Garzon-Muvdi
,
Colette Aprhys
,
Alfredo Quinones-Hinojosa
Keywords(s):
Basic Research Biomarker
,
Brain Cancer
,
Cancers
,
Cell Signaling
,
Cloning Reagents
,
Discovery/Research Tools
,
Disease Indication
,
Glioblastoma
,
Glioma
,
Molecular Switches/Receptors
,
Plasmid
,
Recombinant Proteins
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Proteins, Ligands & Receptors
,
Technology Classifications > Research Tools > Vectors & Plasmids
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Technology Classifications > Research Tools
,
Clinical and Disease Specializations > Oncology > Brain Cancer
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