Search Results - vanessa+merino

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Novel Biomarker for Breast Cancer Detection Outcome and Treatment Sensitization to Nucleolin and CDK Inhibitors

Unmet Need: Despite widespread research efforts, breast cancer remains the second leading cause of cancer deaths in women. There is an urgent need to identify novel biomarkers and treatment strategies against aggressive forms of breast cancer to improve prognosis and therapy. Technical Details: Johns Hopkins researchers have identified a novel biomarker...

Published: 3/14/2025 | Inventor(s): Vanessa Merino, Saraswati Sukumar, Martin Pomper

Keywords(s): Biomarker, Breast Cancer, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics (Old), Prognostic Biomarker, Prostate Cancer

Category(s): Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Diagnostics > Prognostic Biomarkers, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Therapeutic Modalities > Targets

PIK3CA Mutants Transgenic Mouse

C11063: PIK3CA Mutants Transgenic Mouse Technical Details: BACKGROUND Transgenic animals are currently produced as disease models to exhibit disease symptoms so that effective treatment can be studied TECHNOLOGY JHU researchers have generated transgenic mice expressing the hot spot mutations for PI3KCA (H1047R and E545K) specifically in mammary...

Published: 3/13/2025 | Inventor(s): Vanessa Merino, Xiaohui Liang, Saraswati Sukumar

Keywords(s): Basic Research Biomarker, Cell Lines, Discovery/Research Tools, In Vitro Research Tool, In Vivo Research Tool, Mouse Cell Lines, Mouse Model

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools