Search Results - clinical+and+disease+specializations+%3e+neurology+%3e+multiple+sclerosis

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Methods to Treat Neurodegenerative Diseases

Unmet NeedAn estimated 930K people in the US are living with a neurodegenerative disease (Alzheimer’s and Parkinson’s are most common). However, current standard of care treatments mostly addresses symptoms of these diseases. To date no disease modifying or neuroprotective treatments are approved for Parkinson, and only 1 recently has been for Alzheimer’s...

Published: 5/10/2024 | Inventor(s): Rana Rais, Barbara Slusher, Arindom Pal

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Neurology > Alzheimer's Disease, Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Clinical and Disease Specializations > Neurology > Amyotrophic Lateral Sclerosis, Clinical and Disease Specializations > Neurology > HIV-Associated Neurocognitive Disorders

Novel Therapeutic Drug for Multiple Sclerosis

INVENTION NOVELTY This molecule, through its action on a unique target that is different from current therapeutic treatments for MS, has both immunosuppressive and neuromodulatory properties that will better prevent the progression of MS and repair the neuronal damage caused by the immune cells in MS. Currently, there are no MS drugs in the market...

Published: 5/9/2024 | Inventor(s): Paul Kim, Michael Kornberg, Peter Calabresi, Solomon Snyder

Keywords(s): Chronic Inflammatory Diseases, CNS and Neurological Disorders, Disease Indication, Multiple Sclerosis, Multiple Sclerosis (MS), Neurodegeneration, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

3D Shell MEAs for Electrically Active Organoids

Value Proposition· 3D shell MEAs is a novel platform for encapsulation, electrical stimulation, and recording of organoids· Electrophysiological measurements of electrically active 3D organoids. · Relevant to brain development, neurological disorders, drug screening; neuromorphic computing and brain-machine interfaces; and organoid...

Published: 5/10/2024 | Inventor(s): David Gracias, Lena Smirnova, Qi Huang

Keywords(s):

Category(s): Clinical and Disease Specializations > Autoimmunity, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Neurology > Motor Neuron Diseases, Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Clinical and Disease Specializations > Neurology > Neurodegeneration, Clinical and Disease Specializations > Neurology > Neuropathy, Technology Classifications, Technology Classifications > Research Tools > Stem Cells, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Research Stem Cells

Quantitative Human Motion Analysis using Video-based Pose Estimation

Unmet NeedHuman gait analysis is now common in many fields of clinical and basic research, but gold standard approaches – e.g., three-dimensional motion capture, instrumented mats or footwear, and wearables – are often expensive, immobile, data-limited, and/or require specialized equipment or expertise for operation, furthermore limiting the access...

Published: 5/10/2024 | Inventor(s): Ryan Roemmich, Jan Stenum

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Clinical and Disease Specializations > Neurology > Parkinson’s Disease, Clinical and Disease Specializations > Neurology > Stroke, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging

Segmenting retinal OCT images with inter-B-scan and longitudinal information

Unmet NeedA recent study by the National Multiple Sclerosis Society found that nearly one million people are living with multiple sclerosis (MS) in the United States, making it the most common immune-mediated inflammatory demyelinating disease of the nervous system. Due to few disease-specific characteristic symptoms and the varied pace of disease progression...

Published: 5/10/2024 | Inventor(s): Jerry Prince, Yufan He, Aaron Carass

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics > Companion Diagnostics, Technology Classifications > Medical Devices > Imaging

Layer boundary evolution for macular OCT segmentation

Unmet NeedOptical coherence tomography (OCT) is a three-dimensional (3D) imaging technique that emits a beam of light into the tissues to be examined and detects the reflected or back-scattered light from the tissues. OCT produces high-resolution depth images of the retina and is now the standard of care for in vivo ophthalmological assessment. It is...

Published: 5/9/2024 | Inventor(s): Jerry Prince, Aaron Carass, Yihao Liu

Keywords(s): Computer and Network Systems, Computer Software, Image Analysis Software, Image Processing Software, Imaging and Sensing Systems, In Vivo Medical Imaging

Category(s): Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis

Diagnostic and Prognostic Markers and Treatment Strategies for Multiple Sclerosis

C04371: Novel Diagnostic and Prognostic Multiple Sclerosis Protein BiomarkerNovelty: A novel diagnostic and prognostic protein biomarker in Cerebral Spinal Fluid that is 100% specific for Multiple Sclerosis when compared to other neurologic disorders.Value Proposition: Current Multiple Sclerosis diagnosis is produced and confirmed strictly by clinical...

Published: 5/9/2024 | Inventor(s): Caroline Anderson, David Irani, Robert Cotter, Norman Haughey, Joseph Steiner, Avindra Nath

Keywords(s): Biomarker, Chronic Inflammatory Diseases, Clinical Diagnostics, CNS and Neurological Disorders, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Multiple Sclerosis, Multiple Sclerosis (MS), Neurodegeneration, Prognostic Biomarker