Search Results - hybridomas

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Hybridoma expressing anti-RG-1 mAb for the study of human papillomavirus L2

Technology DescriptionJHU scientists generated a hybridoma expressing a monoclonal antibody, RG-1, that binds to highly conserved L2 residues and neutralizes human papillomavirus 16 (HPV16) and HPV18. Passive immunotherapy with RG-1 was protective in mice. Antiserum to the HPV16 L2 peptide comprising conserved residues neutralized pseudoviruses HPV5,...

Published: 5/9/2024 | Inventor(s): Ratish Gambhira, Richard Roden

Keywords(s): Antibodies, Basic Research Biomarker, Cell Model, Discovery/Research Tools, Hybridomas, In Vitro Research Tool, Monoclonal Antibodies, Research Reagent

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools

Hybridoma (MY-31)

TITLE Hybridoma (MY-31) CASE NUMBER C09194 DESCRIPTION CD56, clone MY31, is derived by immunizing (C57BL/6 x BALB/c) F1 mice with the KG1a cell line and fusing the immune splenocytes with the SP2/0 myeloma cell line. CD56 recognizes an antigen present on natural killer (NK) lymphocytes. PUBLICATION Lanier, L.L., Le, A.M., Civin, C.I., Loken,...

Published: 5/9/2024 | Inventor(s): Curt Civin

Keywords(s): Basic Research Biomarker, Cell Model, Discovery/Research Tools, Hybridomas, In Vitro Research Tool

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools

Hybridoma Clone PVALD 434-3 4A4.2E12 or PVALD 434-3 4A4.6B10 Producing Monoclonal Antibody to Pfalciparum Aldolase or Monoclonal Antibody Purified from same Hybridoma

C10647: Monoclonal Antibody to Pfalciparum Aldolase (Hybridoma Clone PVALD 434-3 4A4.2E12 or PVALD 434-3 4A4.6B10) Value Proposition: • This technology has an application to address a major patient need. • The ability to reliably diagnose malaria infections. • The monoclonal antibodies specific to aldolase. Technical Details: Malaria is...

Published: 5/9/2024 | Inventor(s): David Sullivan

Keywords(s): Antibodies, Basic Research Biomarker, Biomarker, Cell Model, Clinical Diagnostics, Diagnostic Biomarker, Discovery/Research Tools, Disease Indication, Hybridomas, In Vitro Diagnostics, In Vitro Research Tool, Infectious Diseases, Malaria, Monoclonal Antibodies, Parasitic Infections, Research Reagent

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Malaria, Clinical and Disease Specializations > Infectious Diseases > Parasitic Infections, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools

Hybridoma Clone G6

C10552: Hybridoma Secreting Anti-Excitatory Amino Acid Transporter 2 (EAAT2) AntibodyNovelty: Hybridoma cell line that secretes monoclonal antibody to GLT1/EAAT2 protein.Value Proposition: Mutations or decreased expression of the GLT1/EAAT2 protein are associated with amyotrophic lateral sclerosis and thus the detection of protein can be used as an...

Published: 5/9/2024 | Inventor(s): Jeffrey Rothstein

Keywords(s): Amyotrophic Lateral Sclerosis, Basic Research Biomarker, Cell Lines, Cell Model, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, Human Cell Lines, Hybridomas, In Vitro Research Tool, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Clinical and Disease Specializations > Rare Diseases, Clinical and Disease Specializations > Neurology > Amyotrophic Lateral Sclerosis, Technology Classifications > Research Tools > Human Cell Lines

CD19 Hybridoma

C09951: Hybridoma Cell Line Secreting Mouse CD19 AntibodyNovelty: Hybridoma cell line (1D3) secreting the monoclonal antibody against the murine homologue of B-cell CD19 protein.Value Proposition: CD19 is a B lymphocyte-lineage antigen and has been associated with cancer progression, notably B-cell lymphomas. Therefore, extensive animal model study...

Published: 5/9/2024 | Inventor(s): Ian Krop, Douglas Fearon

Keywords(s): Basic Research Biomarker, Cell Model, Discovery/Research Tools, Hybridomas, In Vitro Research Tool

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools

R-3327-AT6.1

C03847: R-3327-AT6.1 Technical Details: Somatic cell hybrids created from highly metastatic rat prostatic cancer cells and human chromosome 11 were created using micro cell-mediated chromosome transfer. The introduction of human chromosome 11 into the highly metastatic rat prostate cancer cells suppressed the metastatic ability of the cells without...

Published: 5/9/2024 | Inventor(s): John Isaacs

Keywords(s): Basic Research Biomarker, Cell Model, Discovery/Research Tools, Hybridomas, In Vitro Research Tool

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Research Tools, Technology Classifications > Therapeutic Modalities

Hybridoma H5C6

C03188: Hybridoma H5C6 Technical Details: A murine hybridoma cell line that secretes a monoclonal antibody (IgG1, k) against hum CD63.Looking for Partners: Useful tool for immunophenotyping, immunohistochemistry, immunoprecipitation, Western blot analysis, and immunocapture assays.Publications:Blood 1991 77:121-132

Published: 5/9/2024 | Inventor(s): James Hildreth

Keywords(s): Antibodies, Basic Research Biomarker, Cell Model, Discovery/Research Tools, Hybridomas, In Vitro Research Tool, Monoclonal Antibodies, Research Reagent

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools