Search Results - pei-hsun+wu

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Phenotypic Microarray for Diagnosis of Cancer

Invention novelty: High Throughput Screening of pancreatic cancer cells by developing a phenotypic microarray Value Proposition: The market for cancer diagnostics is ever-expanding as the focus of global research on cancer reached its peak in the past five years. The use of microarrays as an ideal diagnostic tool for cancer detection is being realized...

Published: 5/9/2024 | Inventor(s): Denis Wirtz, Pei-Hsun Wu, Shyam Khatau, Wei-Chiang Chen, Zev Binder, Jude Phillip, Yiider Tseng

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics, In Vitro Research Tool, Pharmakodynamic Biomarker, Prognostic Biomarker, Target-based Screening Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > Prognostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics, Technology Classifications > Research Tools > Assays

Computational method for the 3D reconstruction and multi-labelling of serially sectioned tissue

Unmet Need / Invention Novelty: Three-dimensional (3D) tissue reconstruction permits analyses of the relationships between cellular factors, tissue structure, and diseasepathology.Current methods used to visualize and quantify tissue structures in 3D space are limited to small volumes and have various constraints relating to consistency, information...

Published: 5/10/2024 | Inventor(s): Denis Wirtz, Ashley Kiemen, Pei-Hsun Wu, Ralph Hruban, Laura Wood, Alexandra Sneider, Luo Gu, Mehran Habibi, Joo Ho Kim

Keywords(s):

Category(s): Technology Classifications > Research Tools

Workflow for Targeted Analysis of Image Mass Cytometry

Technology Description· Researchers at Johns Hopkins have developed a streamlined workflow for performing targeted imaging in image mass cytometry (IMC) with improved region of interest (ROI) selection. · This approach for ROI identification uses adjacent stained sections (e.g., H&E, PAS) with more prominent tissue features as a guide.· ROI...

Published: 5/10/2024 | Inventor(s): Pei-Hsun Wu, Denis Wirtz, Won Jin Ho

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Imaging

Comprehensive Phenotyping Reveals Robust Determination to Cellular Biological Age

Technology OverviewJHU researchers have developed a platform to determine the cellular biological age of individuals based on quantifiable functional outputs of their cells. Using a comprehensive approach, of high-throughput single cell technologies to measure biochemical and biophysical properties of cells, we have further developed a generalized linear...

Published: 5/9/2024 | Inventor(s): Jude Phillip, Denis Wirtz, Pei-Hsun Wu, Jeremy Walston

Keywords(s): Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Discovery/Research Tools, In Vitro Research Tool, Physics, Research Instrument

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Research Tools