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Fibrillin 1 Mutant Mice (W1572C Mutant Strain) and (D1545E Mutant Strain)

TITLE: Fibrillin 1 Mutant Mice (W1572C Mutant strain) and (D1545E Mutant Strain)CASE NUMBER: C13499ABSTRACTFibrillin1 D1545E Mutant StrainThese mice carry a D1545E mutation in the mouse Fbn1 gene and serve as a model of human stiff skin syndrome with increased collagen deposition in the dermis, decreased subcutaneous fat, and circulating anti-nuclear...

Published: 3/13/2025 | Inventor(s): Harry Dietz, Elizabeth Gerber

Keywords(s): Basic Research Biomarker, Cell Lines, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, In Vivo Research Tool, Knock In Mouse Model, Mouse Cell Lines, Mouse Model, Skin Disorders, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Clinical and Disease Specializations > Dermatology