Search Results - fly+model

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C11872: Novel Method to Visualize Cells that Undergo Apoptosis Reversal

Value Proposition: This biosensor may be used to identify anastasis events in animals or cells, in screens to identify genes/protein/RNAs that modulate anastasis or in screens for small molecules that potentiate or inhibit anastasis. Technology advantages: - This biosensor can be used to label cells in vivo or in vitro. - This technology permanently...

Published: 7/4/2024 | Inventor(s): Ho Lam Tang, Denise Montell

Keywords(s): Discovery/Research Tools, Fly Model, Imaging and Sensing Systems, In Vitro Research Tool, In Vivo Medical Imaging, Labels/Markers, Research Reagent

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices, Technology Classifications > Research Tools

Candidatus Rickttsia Amblyommii in Cell Culture

C11709: Tick-Associated Pathogen Candidatus Rickettsia Amblyommii in Cell CultureNovelty: Cell Culture of the bacterium Candidatus Rickettsia amblyommii from lone star ticks for research studies.Value Proposition: The lone star tick is a broadly distributed wild tick that has been recently found to transmit the bacterial pathogen Cadidatus Rickettsia...

Published: 7/4/2024 | Inventor(s): Jason Rasgon, Douglas Norris

Keywords(s): Bacterial Infections, Basic Research Biomarker, Cell Lines, Discovery/Research Tools, Disease Indication, Fly Model, In Vitro Research Tool, Infectious Diseases

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections

Identification of Chromosome 1 and Chromosome 19 Genes Contributing to Oligodendrogliomagenesis

C11619: Novel Molecular Diagnostic for Brain CancerNovelty: The invention is novel genetic mutations to genes CIC and FUBP1 not previously associated with oligodendrogliomagenesis, the second most common malignant brain tumor type in adults.Value Proposition: The inventors indentified unreported changes in a gene’s amino acid sequence that appears...

Published: 7/4/2024 | Inventor(s): Bert Vogelstein, Kenneth Kinzler, Nickolas Papadopoulos, Nishant Agrawal, Chetan Bettegowda, Darell Bigner, Hai Yan, Roger Mclendon

Keywords(s): Biomarker, Brain Cancer, Cancers, Clinical Diagnostics, CNS and Neurological Disorders, Diagnostic Biomarker, Discovery/Research Tools, Disease Indication, Fly Model, In Vitro Diagnostics (Old), In Vitro Research Tool, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology > Brain Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Clinical and Disease Specializations > Neurology

LRRK2 Fly Model for Parkinson's Disease WT1 and GS2 Flies

C10263: LRRK2 Fly Model for Parkinson's Disease Technical Details: Mutations in the leucine rich repeat kinase (LRRK2) gene causes late onset autosomal dominant Parkinson's disease (PD). The LRR protein has two enzyme activities (kinase and GTPase) which play important roles in regulating neuronal death and other cellular functions. We have...

Published: 7/4/2024 | Inventor(s): Wanli Smith

Keywords(s): Basic Research Biomarker, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, Fly Model, In Vitro Research Tool, Parkinson's Disease

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Parkinson's Disease, Technology Classifications > Research Tools > Animal Models, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools