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Generation of Human Cell Lines with Genetic Inactivation of PDPK1

C12018: Novel Human PDPK1, AKT1, and AKT2 Knock-out Cell Lines for Studying CancerNovelty: Development of modified human cancer cell lines with inactivated PDPK1 gene for studying colon cancer.Value Proposition: Modified human cell lines serve as useful research tools for studying the pathophysiology and cellular level differences between normal cells...

Published: 3/13/2025 | Inventor(s): Christine Gan, Nickolas Papadopoulos, Kajsa Ericson, Victor Velculescu, Kenneth Kinzler, Bert Vogelstein

Keywords(s): Basic Research Biomarker, Cell Lines, Discovery/Research Tools, Human Cell Lines, In Vitro Research Tool

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools

AKT1 and AKT2 KO Cells

C10770: AKT1 and AKT2 KO CellsValue Proposition: Cell Lines AKT1-/- (D3A8G5) in HCT116 AKT1-/- (H1D1A12) in HCT116 AKT1-/-, AKT2-/- (HDK1-B2-F12-E5) in HCT116 AKT1-/-, AKT2-/- (HDK2-E1-B2-G3) in HCT116 AKT2-/- (A10A5C6) HCT116 in HCT116 AKT2-/- (C12B8B5) HCT116 in HCT116 AKT1-/- (D6D7A12) in DLD1 AKT1-/- (G10C3C5) in DLD1 AKT1-/-, AKT2-/- (DDK3-C2-G4-H2)...

Published: 3/13/2025 | Inventor(s): Victor Velculescu, Kajsa Ericson, Kenneth Kinzler, Nickolas Papadopoulos, Bert Vogelstein

Keywords(s): Basic Research Biomarker, Cancer Cells, Cancers, Cell Lines, Cell Model, Colorectal Cancer, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Research Tools > Human Cell Lines