Search Results - kam+leong

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Functional Fibers for Ex Vivo Expansion of Stem and Progenitor Cells

NeedUmbilical cord blood is a promising alternative source of hematopoietic stem/progenitor cells (HSPCs) for allogeneic and autologous hematopoietic stem cell transplantation for the treatment of a variety of hematological disorders and as supportive therapy for malignant diseases. However, the low number of HSPCs obtainable from a single donor restricts...

Published: 3/13/2025 | Inventor(s): Kam Leong, Kian-Ngiap Chua, Seeram Ramakrishna, Hai-Quan Mao

Keywords(s): Basic Research Biomarker, Cell Model, Discovery/Research Tools, In Vitro Research Tool, Stem Cells

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Stem Cells, Technology Classifications > Research Tools

An Insulin-loaded Nanoparticle and the Method for Preparing Thereof

Unmet Need:Repeated injections of insulin is the standard of care for treating Type 1 diabetes, and essential for control and management of Type 2 diabetes. Drawbacks of this treatment include poor patient compliance, discomfort, and an impaired lifestyle, and hypoglycemia. Oral administration of insulin, if successful, could deliver insulin such that...

Published: 3/13/2025 | Inventor(s): Hai-Quan Mao, Jose Santos, Zhiyu He, Huahua Huang, Lixin Liu, Kam Leong, Yongming Chen

Keywords(s): Diabetes, Disease Indication, Drug Delivery Vehicle, Metabolic Disorders, Nanoparticles, Therapeutic Matter, Therapeutic Method, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Diabetes, Clinical and Disease Specializations > Metabolic Diseases, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms