Search Results - kelvin+liu

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miRNA Analysis Method

#C11885: miRNA Analysis MethodUnmet NeedThe gold standard for miRNA profiling is quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). While qRT-PCR is fast, reproducible, and can handle smaller input samples than other profiling methods (Chugh et al.), it can only evaluate less than 10 miRNAs at a time. Other methods can profile thousands...

Published: 6/27/2024 | Inventor(s): Yunke Song, Kelvin Liu, Tza-Huei Wang

Keywords(s): Assay, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Technology Classifications > Research Tools

Single Molecule Free Solution Hydrodynamic Separation Platform

A method of separating, detecting and determining a size of each of a plurality of particles in a fluid includes compelling the fluid to flow through a fluid channel such that larger particles of the plurality of particles travel through the fluid channel faster than smaller particles of the plurality of particles; illuminating a detection zone of the...

Published: 6/27/2024 | Inventor(s): Kelvin Liu, Tza-Huei Wang

Keywords(s): Discovery/Research Tools, In Vitro Research Tool, Research Instrument

Category(s): Technology Classifications > Research Tools

Microfluidic Solution for High-throughput, Droplet-based Single Molecule Analysis with Low Reagent Consumption

A microfluidic device for a confocal fluorescence detection system has an input channel defined by a body of the microfluidic device, a sample concentration section defined by the body of the microfluidic device and in fluid connection with the input channel, a mixing section defined by the body of the microfluidic device and in fluid connection with...

Published: 6/27/2024 | Inventor(s): Christopher Puleo, Kelvin Liu, Tushar Rane, Tza-Huei Wang

Keywords(s): Assay, Clinical Diagnostics, Discovery/Research Tools, In Vitro Diagnostics, In Vitro Research Tool, Microfluidic, Research Instrument

Category(s): Technology Classifications > Research Tools, Technology Classifications > Research Tools > Microfluidics

DNA integrity assay (DIA) for cancer diagnostics, using confocal fluorescence spectroscopy

Value Proposition: Traditional DNA integrity testing relies on real time PCR to amplify a limited number of chromosomal loci and determine the relative proportions of segments. This suffers from biased amplification that will skew the distribution of DNA lengths and make accurate determination of concentrations difficult. In addition, PCR based methods...

Published: 6/27/2024 | Inventor(s): Kelvin Liu, Ie-Ming Shih, Tza-Huei Wang

Keywords(s): Assay, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics

CYLINDRICAL ILLUMINATION CONFOCAL SPECTROSCOPY

Unmet Need / Invention Novelty: Confocal single molecule detection (SMD) is a spectroscopic technique that plays a significant role in biological research due to its unique ability to detect and investigate the discrete properties of individual biomolecules. However, current implementations of SMD suffer from low throughput and quantification accuracy...

Published: 6/27/2024 | Inventor(s): Kelvin Liu, Tza-Huei Wang

Keywords(s): Clinical Diagnostics, Diagnostic System, Discovery/Research Tools, In Vitro Diagnostics, In Vitro Research Tool, Research Instrument

Category(s): Technology Classifications > Research Tools, Technology Classifications > Diagnostics > In Vitro Diagnostics