Search Results - diagnostic+system

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Unmet NeedCirculating tumor cells (CTCs) are cancer cells that have left the primary tumor and are carried around the body in circulation. Because their numbers are small, they are not easily detected. Through CTC capture, valuable information can be uncovered regarding a tumor’s link to cancer diagnosis or treatment. One method of detecting CTCs is...

Published: 6/27/2024 | Inventor(s): Dan Stoianovici, Doru Petrisor, Changhan Jun, Kenneth Pienta

Keywords(s): Cancers, Clinical Diagnostics, Diagnostic System, Disease Indication, In Vitro Diagnostics

Category(s): Technology Classifications > Diagnostics > In Vitro Diagnostics, Clinical and Disease Specializations > Oncology

DEVICES AND METHODS FOR MAGNETIC ISOLATION AND ANALYSIS OF RARE CELLS

Unmet NeedNumerous devices and methods have been developed to try and isolate circulating tumor cells in a reproducible and efficient manner. To date, the majority of work has been performed utilizing the CellSearch test, which is the only FDA-approved device. However, the CellSearch test is limited by the associated expense and not being able to be...

Published: 6/27/2024 | Inventor(s): Dan Stoianovici, Kenneth Pienta, Michael Gorin

Keywords(s): Cancers, Clinical Diagnostics, Diagnostic System, Disease Indication, In Vitro Diagnostics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics

Multifunctional Nanoprobe-enabled Capture and Early Detection of Microbial Pathogens

Unmet NeedConventional monitoring of food safety and environment relies on laboratory based biochemical methods such as PCR and ELISA assays. While these methods are well established and possess high sensitivity and specificity, they are time consuming, laborious, require skilled personnel, sophisticated facilities and strict cleaning standards, which...

Published: 6/27/2024 | Inventor(s): Chao Wang, Kellogg Schwab, Charles Young

Keywords(s): Bacterial Infections, Clinical Diagnostics, Diagnostic System, Disease Indication, In Vitro Diagnostics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases

Self-contained Cartridge and Methods for Integrated Biochemical Assay at the Point-of-care

We report a self-contained, miniaturized biochemical assay platform for nucleic acid testing of infectious agents from biological fluids. Our work utilizes a sealed plastic cartridge with patterned surfaces for reagent storage and fluidic processing. Biochemical reactions including nucleic acid amplification tests are performed with a colorimetric readout....

Published: 6/27/2024 | Inventor(s): Dong Shin, Tza-Huei Wang

Keywords(s): Assay, Clinical Diagnostics, Diagnostic System, In Vitro Diagnostics

Category(s): Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Technology Classifications > Research Tools

CYLINDRICAL ILLUMINATION CONFOCAL SPECTROSCOPY

Unmet Need / Invention Novelty: Confocal single molecule detection (SMD) is a spectroscopic technique that plays a significant role in biological research due to its unique ability to detect and investigate the discrete properties of individual biomolecules. However, current implementations of SMD suffer from low throughput and quantification accuracy...

Published: 6/27/2024 | Inventor(s): Kelvin Liu, Tza-Huei Wang

Keywords(s): Clinical Diagnostics, Diagnostic System, Discovery/Research Tools, In Vitro Diagnostics, In Vitro Research Tool, Research Instrument

Category(s): Technology Classifications > Research Tools, Technology Classifications > Diagnostics > In Vitro Diagnostics

Biosensor for Measuring Substances in Circulating Blood

C11789: Unique Biosensor for Continuous Monitoring of Circulating BiomarkersNovelty: The technology presents a novel transistor-based biosensor design for continuous monitoring of circulating biomarkers in blood or urine that can be used for clinical diagnosis, point of care (POC) assays, and patient monitoring.Value Proposition: There is currently...

Published: 6/27/2024 | Inventor(s): Howard Katz, Kalpana Besar, Weiguo Huang, Allen Everett

Keywords(s): Blood Disorder, Cardiovascular Diseases, Clinical Diagnostics, Diagnostic System, Disease Indication, Imaging and Sensing Systems, In Vitro Diagnostics, In Vivo Medical Imaging, Medical Sensor

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Hematology, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

Method for Finding Mutations Caused by the Insertion of Repeated DNAs

C04260: Method for Finding Mutations Caused by the Insertion of Repeated DNAsNovelty: This invention provides a novel method for identifying repeat insertion mutations, useful for identifying or classifying genetic diseases, and mapping complex traits controlled by repeat insertions.Value Proposition: Currently available human mutation detection methods,...

Published: 6/27/2024 | Inventor(s): Jef Boeke

Keywords(s): Cancers, Clinical Diagnostics, CNS and Neurological Disorders, Diagnostic System, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics, In Vitro Research Tool, Research Instrument

Category(s): Technology Classifications > Research Tools, Technology Classifications > Diagnostics > In Vitro Diagnostics, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Neurology