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Search Results - leslie+tung
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Grid of Responses Indicating Drug Sensitivity
Unmet NeedDrug development is a long and costly process characterized by a high degree of attrition. Cardiotoxicity is the most common reason for withdrawing candidate drugs from the development pipeline, with 30% of drugs withdrawn during the clinical development phase. Improvements in methodologies for assessing drug cardiotoxicity during preclinical...
Published: 3/14/2025
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Inventor(s):
Leslie Tung
,
Adriana Blazeski
Keywords(s):
Assay
,
Clinical Diagnostics
,
Discovery/Research Tools
,
In Vitro Diagnostics (Old)
,
In Vitro Research Tool
,
Research Instrument
Category(s):
Technology Classifications > Diagnostics > In Vitro Diagnostics
,
Technology Classifications > Research Tools > Assays
Engineered Heart Slices
Engineered Heart SliceJHU REF: C12744Invention Novelty: A novel method of producing acellular cardiac tissue scaffolds with stem-cells for tissue regeneration productsValue Proposition: Tissue constructs using cardiac cells and a base matrix have been developed in the past, and several methods of creating these constructs have been described. However...
Published: 3/13/2025
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Inventor(s):
Adriana Blazeski
,
Leslie Tung
Keywords(s):
Basic Research Biomarker
,
Buffer/Media Solution
,
Culture Media
,
Discovery/Research Tools
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Buffers & Media Solutions
,
Technology Classifications > Research Tools
,
Clinical and Disease Specializations > Cardiovascular
Method for Termination of Cardiac Fibrillation and Tachycardia
C10844: Gentler Method for Termination of Cardiac ArrhythmiasNovelty: A method to prevent cardiac sudden death by delivering a high frequency current or electric field to the myocardium, with less associated damage to the heart.Value Proposition: Currently the only reliable way to terminate fibrillation is by delivering a high voltage DC shock to cause...
Published: 3/13/2025
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Inventor(s):
Harikrishna Tandri
,
Ronald Berger
,
Leslie Tung
,
Henry Halperin
,
David Hunter
,
Seth Weinberg
Keywords(s):
Arrhythmias
,
Cardiovascular Diseases
,
Disease Indication
,
Electrical Stimulation Device
,
Implanted Device
,
Implants
,
Therapeutic Devices
,
Therapeutics
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Cardiovascular > Arrhythmias
,
Technology Classifications > Medical Devices > Therapeutic Devices
,
Clinical and Disease Specializations > Cardiovascular
,
Technology Classifications > Medical Devices
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