Search Results - ligand

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Siglec-8 Ig Fusion Protein and Cell Line Secreting It; Transfected HEK & RBL Cell Lines Stably Expressing Siglec-8 on their Surface
Development of Siglec-8 fusion protein and expression of the protein in HEK & RBL cell lines.JHU REF: [C11910]Invention novelty: Development of novel fusion protein Siglec-8 and its expression in animal cell lines HEK and RBL.  Value Proposition:Siglec-8, formerly named SAF-2 is a 431–amino acid protein composed of 3 Ig domains with a 358–amino...
Published: 10/23/2025   |   Inventor(s): Bruce Bochner
Keywords(s): Basic Research Biomarker, Cell Signaling, Discovery/Research Tools, Ligand, Research Reagent
Category(s): Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools
Neuropilin-1 Sema Mice
Value Proposition:Extended Survival for Research: Unlike mice that completely lack Npn-1 and die early in development, these mice live until birth, making them more useful for studying how Npn-1 functions in living systems.Tool for Mechanistic Studies: The gene replacement strategy provides a unique model to dissect the roles of semaphorin vs. VEGF...
Published: 10/23/2025   |   Inventor(s): David Ginty
Keywords(s): Cell Signaling, Discovery/Research Tools, In Vivo Research Tool, Knock Out Mouse Model, Ligand, Molecular Switches/Receptors, Mouse Model, Research Reagent, Translational Research Biomarker
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools
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