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Siglec-8 Ig Fusion Protein and Cell Line Secreting It; Transfected HEK & RBL Cell Lines Stably Expressing Siglec-8 on their Surface

Development of Siglec-8 fusion protein and expression of the protein in HEK & RBL cell lines.JHU REF: [C11910]Invention novelty: Development of novel fusion protein Siglec-8 and its expression in animal cell lines HEK and RBL. Value Proposition:Siglec-8, formerly named SAF-2 is a 431–amino acid protein composed of 3 Ig domains with a 358–amino...

Published: 3/13/2025 | Inventor(s): Bruce Bochner

Keywords(s): Basic Research Biomarker, Cell Signaling, Discovery/Research Tools, Ligand, Research Reagent

Category(s): Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools

Neuropilin-1 Sema Mice

C04679: Neuropilin-1 Sema Mice Technical Details: Neuropilin-1 (Npn-1) is a receptor that binds ligands from structurally distinct families like semaphorins (Sema) and vascular endothelial growth factors (VEGF). Npn-1 is a type I transmembrane protein with a small cytoplasmic domain and multiple extracellular domains capable of mediating a variety...

Published: 3/13/2025 | Inventor(s): David Ginty

Keywords(s): Cell Signaling, Discovery/Research Tools, In Vivo Research Tool, Knock Out Mouse Model, Ligand, Molecular Switches/Receptors, Mouse Model, Research Reagent, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools