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Search Results - ligand
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Siglec-8 Ig Fusion Protein and Cell Line Secreting It; Transfected HEK & RBL Cell Lines Stably Expressing Siglec-8 on their Surface
Development of Siglec-8 fusion protein and expression of the protein in HEK & RBL cell lines.JHU REF: [C11910]Invention novelty: Development of novel fusion protein Siglec-8 and its expression in animal cell lines HEK and RBL. Value Proposition:Siglec-8, formerly named SAF-2 is a 431–amino acid protein composed of 3 Ig domains with a 358–amino...
Published: 10/23/2025
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Inventor(s):
Bruce Bochner
Keywords(s):
Basic Research Biomarker
,
Cell Signaling
,
Discovery/Research Tools
,
Ligand
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Proteins,
Ligand
s & Receptors
,
Technology Classifications > Research Tools
Neuropilin-1 Sema Mice
Value Proposition:Extended Survival for Research: Unlike mice that completely lack Npn-1 and die early in development, these mice live until birth, making them more useful for studying how Npn-1 functions in living systems.Tool for Mechanistic Studies: The gene replacement strategy provides a unique model to dissect the roles of semaphorin vs. VEGF...
Published: 10/23/2025
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Inventor(s):
David Ginty
Keywords(s):
Cell Signaling
,
Discovery/Research Tools
,
In Vivo Research Tool
,
Knock Out Mouse Model
,
Ligand
,
Molecular Switches/Receptors
,
Mouse Model
,
Research Reagent
,
Translational Research Biomarker
Category(s):
Technology Classifications > Research Tools > Animal Models
,
Technology Classifications > Research Tools > Proteins,
Ligand
s & Receptors
,
Technology Classifications > Research Tools
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