Search Results - miguel+garcia-gonzalez

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1. Pkd2(tm1Tjw) Mouse line 2. Pkd2(tm1.1Tjw) 3. Pkd2(tm1.2Tjw) 4. Pkd2(tm1.3Tjw) 5. Pkd2(tm1.4Tjw)

C11274: Mouse Model to study Human Autosomal Dominant Polycystic Kidney Disease.Value Proposition: Inventors disclose five mouse lines with loxP sites introduced into introns 10 and 13 of the mouse Pkd2 gene that allow its regulated inactivation using inducible Cre-recombinases. This mouse model can mimic the features of human autosomal dominant polycystic...

Published: 3/13/2025 | Inventor(s): Gregory Germino, Miguel Garcia-Gonzalez, Terry Watnick

Keywords(s): Basic Research Biomarker, Cell Lines, Discovery/Research Tools, In Vitro Research Tool, Mouse Cell Lines

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools

Line 1: Pkhd1flox3-4 mouse line, formal name Pkhd1tm1Ggg.; Pkhd1del3-4 mouse line, formal name Pkhd1tm1Ggg.1

C04916: Line 1: Pkhd1flox3-4 mouse line, formal name Pkhd1tm1Ggg.; Pkhd1del3-4 mouse line, formal name Pkhd1tm1Ggg.1 Technical Details: Pkhd1flox3-4, when mutated, causes human autosomal recessive polycystic kidney disease (ARPKD). The Pkhdlde13-4 allele results after Cre-mediated deletion of exons 3 and 4. Homozygosity for this allele results in a...

Published: 3/13/2025 | Inventor(s): Junya Kaimori, Miguel Garcia-Gonzalez, Luis Menezes, Gregory Germino

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools