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Germline and Conditional Deletion of Tardbp

C11168: A Gene Linked to Obesity, and Alters Body Fat Metabolism Value Proposition: • Identifies novel therapeutic target to control obesity and diabetes. • Helps to understand incurable diseases: frontal temporal dementia and amyotrophic lateral sclerosis. Technical Details: JHU scientists have developed conditional knockout mice...

Published: 3/13/2025 | Inventor(s): Donald Price, Po-Min Chiang, Philip Wong

Keywords(s): Amyotrophic Lateral Sclerosis, Basic Research Biomarker, Biomarker, Cell Model, Clinical Diagnostics, CNS and Neurological Disorders, Dementia, Diabetes, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics, In Vitro Research Tool, In Vivo Research Tool, Knock Out Mouse Model, Mechanism-of-action Biomarker, Metabolic Disorders, Mouse Model, Neurodegeneration, Obesity, Stem Cells

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Diabetes, Clinical and Disease Specializations > Metabolic Diseases, Clinical and Disease Specializations > Metabolic Diseases > Obesity, Clinical and Disease Specializations > Neurology > Amyotrophic Lateral Sclerosis, Clinical and Disease Specializations > Neurology > Dementia, Clinical and Disease Specializations > Neurology > Neurodegeneration, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Neurology, Technology Classifications > Therapeutic Modalities, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Stem Cells