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Kinetically controlled methods to prepare concentrated shelf-stable nucleic acid transfection vehicles

Value Proposition:· Technology creates particles optimally size for use as vehicles for cell transfection.· The reagents and processes for particle creation are kinetically controlled and reproducible.· Cationic particles created using these methods can carry larger payloads than current vehicles.· Reagents and nucleic acid-loaded...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Yizong Hu, Jinghan Lin

Keywords(s):

Isolation of Fungal Melanin Granules from Culture Supernatants

Unmet NeedMelanins are multifunctional pigments that have applications in numerous fields, including drug development, radioprotection, bioremediation, solar power, and cosmetics. Melanin pigments have broad optical absorption and are capable of absorbing ionizing radiation. Melanin pigments also have powerful antioxidant activity and are capable of...

Published: 3/14/2025 | Inventor(s): Radames Cordero, Arturo Casadevall, Raghav Vij

Keywords(s): Bioreactor-based Manufacturing, Discovery/Research Tools, In Vitro Research Tool, Industrial Manufacturing, Yeast Model

Category(s): Technology Classifications > Industrial Tech > Bioreactors, Technology Classifications > Engineering Tech > Bioreactors

SpinΩ – A Multi-well Bioreactor for Culturing 3D Organoids

UNMET NEEDSpinning bioreactors have been used for three-dimensional (3D) cell culture and generation of organ-like tissues (organoids). However, current spinning bioreactors available on the market (e.g. the Corning® disposable spinner flasks) have several major challenges including requiring a large volume of medium and incubator space, large sample-to-sample...

Published: 3/13/2025 | Inventor(s): Hongjun Song, Guo-li Ming, Mingxi Song, Christopher Hadiono, William Jeang, Ha Nam Nguyen, Xuyu Qian

Keywords(s): Bioreactor-based Manufacturing, Cell Model, Discovery/Research Tools, In Vitro Research Tool, Industrial Manufacturing, Research Instrument, Stem Cells

Category(s): Technology Classifications > Research Tools, Technology Classifications > Industrial Tech > Bioreactors, Technology Classifications > Industrial Tech > Industrial Manufacturing, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Stem Cells, Technology Classifications > Industrial Tech, Technology Classifications > Engineering Tech > Bioreactors, Technology Classifications > Engineering Tech > Industrial Manufacturing