Search Results - yeast+model

7 Results

Sort By:

Isolation of Fungal Melanin Granules from Culture Supernatants

Unmet NeedMelanins are multifunctional pigments that have applications in numerous fields, including drug development, radioprotection, bioremediation, solar power, and cosmetics. Melanin pigments have broad optical absorption and are capable of absorbing ionizing radiation. Melanin pigments also have powerful antioxidant activity and are capable of...

Published: 6/27/2025 | Inventor(s): Radames Cordero, Arturo Casadevall, Raghav Vij

Keywords(s): Bioreactor-based Manufacturing, Discovery/Research Tools, In Vitro Research Tool, Industrial Manufacturing, Yeast Model

Category(s): Technology Classifications > Industrial Tech > Bioreactors, Technology Classifications > Engineering Tech > Bioreactors

A CRISPR-based yeast two-hybrid system for investigating RNA-protein interaction

Unmet Need: DNA-sequencing technology has led to the development of many powerful techniques, such as RIP-seq and CLIP-seq, which can be used to identify many RNAs bound by a protein of interest, however, few protocols exist for identifying the proteins bound to a particular RNA. Most available techniques involve RNA pull-down followed by protein identification...

Published: 6/26/2025 | Inventor(s): David Zappulla, Evan Hass

Keywords(s): Analytical Method, Assay, Clinical Diagnostics, Discovery/Research Tools, In Vitro Diagnostics, In Vitro Research Tool, Target-based Screening Tool, Yeast Model

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics

SUB280 Yeast with Hygromycin Marker at LEU2

An Ubiquitin Expressed Yeast Strain at LEU2 JHU REF: [C12803]Invention Novelty: A genetically engineered single ubiquitin expressed Yeast strain at (leucine) LEU2 to serve as an in vivo model for the discovery of ubiquitin linkage roles in subcellular signal pathways Value Proposition: Unique Polyubiquitination (polyUb) linkage combinations serve essential...

Published: 6/26/2025 | Inventor(s): Eric Cooper, Robert Cohen

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vitro Research Tool, Yeast Model

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Yeast Model

Super Two Micron Plasmid Vectors for Yeast

Value Proposition: A major limitation to efficient production of proteins in yeast has been vector systems that consistently yield large amounts of recombinant protein. Whereas yields of 20-50% of total protein can readily be attained in bacterial systems, yeast systems typically yield 1-2%, and only occasionally as high as 5%. Yet yeast is highly desirable...

Published: 6/26/2025 | Inventor(s): Jef Boeke

Keywords(s): Basic Research Biomarker, Cloning Reagents, Discovery/Research Tools, In Vitro Research Tool, Plasmid, Research Reagent, Yeast Model

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Vectors & Plasmids, Technology Classifications > Research Tools

Suppressors of p53 Cancer Mutations & Genetic Assays and Strains using Human TP53

C09941: Suppressors of p53 Cancer Mutations & Genetic Assays and Strains using Human TP53 Technical Details: The technology concerns the identification of second-site suppressor mutations that can act as Aglobal suppressors@ to overcome the deleterious effects of common p53 cancer mutations responsible for more than 50% of all cancers. Such suppressor...

Published: 6/26/2025 | Inventor(s): Rainer Brachmann, Jef Boeke

Keywords(s): Basic Research Biomarker, Cancers, Cloning Reagents, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Oncogene, Research Reagent, Yeast Model

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Nucleic Acids, Technology Classifications > Research Tools

Wild-Type Amyloid Precursor Protein Yeast Artificial Chromosome Transgenic Line Py8.9

C04586: Wild-Type Amyloid Precursor Protein Yeast Artificial Chromosome Transgenic Line Py8.9 Technical Details: Researchers at Johns Hopkins and Case Western Reserve University have generated a transgenic mouse (Py8.9) line that expresses the wild-type human Amyloid Precursor Protein (APP). This mouse was generated through the insertion of a Yeast...

Published: 6/26/2025 | Inventor(s): Bruce Lamb, John Gearhart

Keywords(s): Basic Research Biomarker, Cell Lines, Discovery/Research Tools, In Vitro Research Tool, Mouse Cell Lines, Yeast Model

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools

pNB1 + pNB3

C04005: pNB1 + pNB3 Technical Details: These molecular biology research tools are recombinant yeast plasmids that were designed for use with an in vitro Tn7 transposition systemLooking for Partners: Genome analysis, characterization and manipulation.

Published: 6/26/2025 | Inventor(s): Nurjana Bachman, Jef Boeke

Keywords(s): Basic Research Biomarker, Cloning Reagents, Discovery/Research Tools, In Vitro Research Tool, Plasmid, Research Reagent, Yeast Model

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Vectors & Plasmids, Technology Classifications > Research Tools