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Methods for in situ Detection of DNA Sequence Variation

Value Proposition· High-throughput· Assess genetic variants with simultaneous spatial analysis· Interrogate over 100 variants in a single assayUnmet Need· Next generation sequencing has led to an ever-proliferating dearth of genetic information. More recent progress in nucleoside tissue analysis has birthed the field of spatial...

Published: 3/14/2025 | Inventor(s): Reza Kalhor, Soichiro Asami

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Category(s): Technology Classifications, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Bioinformatics, Technology Classifications > Research Tools > Imaging, Technology Classifications > Research Tools > Nucleic Acids

Compute Align

A newly invented DNA alignment algorithm combined and fine tuned with recent advances in GPU technology resulted in a 40x 50 x speed increase and better quality results. Bundled with appropriate HW+SW environment, one Compute Align appliance is expected to provide the same speed of data processing capability as the highest speed input data provider,...

Published: 3/13/2025 | Inventor(s): Richard Wilton, Tamas Budavari, Benjamin Langmead, Steven Salzberg, Sandor Szalay

Keywords(s): Computing; Calculating; Counting, Discovery/Research Tools, Electrical Digital Data Processing, In Silico Research Tool, Physics

Category(s): Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Research Tools > Bioinformatics