Search Results - joint+disorders

5 Results

Sort By:

Hexosamine Analogs for Regenerative Medicine and Diseases Associated with the Musculoskeletal System

Unmet Need:Osteoarthritis (OA) is the most common form of arthritis, affecting an estimated 32.5 million adults in the United States, with an increasing incidence as the population ages (see CDC) . OA is associated with considerable morbidity as a consequence of joint damage, resulting in pain, loss of joint range of motion, and disability. The disease...

Published: 5/9/2024 | Inventor(s): Kevin Yarema, Jennifer Elisseeff, Jeannine Coburn, Udayanath Aich

Keywords(s): Antagonists/Inhibitors, Arthritis, Biologics, Carbohydrates, Disease Indication, Drug Delivery Mechanism, Drug Delivery Vehicle, Joint Disorders, Novel, Osteoarthritis, Predicted Novelty, Single, Small Molecules, Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities > Targets, Clinical and Disease Specializations > Rheumatology, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Rheumatology > Arthritis, Clinical and Disease Specializations > Rheumatology > Osteoarthritis

Prostaglandin E2 Mediates Sensory Nerve for Bone Formation and Pain of Skeletal Diseases

Unmet NeedMore than 50 million US adults are affected by arthritis, a joint disorder that can result in persistent pain. There is no cure for arthritis, and in the end stages of the disease, joint replacement is often needed. Current approaches to treat arthritis aim to control pain via the use of analgesics and nonsteroidal anti-inflammatory drugs...

Published: 5/9/2024 | Inventor(s): Xu Cao

Keywords(s): Arthritis, Disease Indication, Joint Disorders, Osteoarthritis, Target, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations > Rheumatology > Osteoarthritis, Technology Classifications > Therapeutic Modalities > Targets

Therapeutic Treating or Preventing Enthesopathy

Unmet NeedOver half of sports injuries involve tendons and entheses (the sites of attachment between ligament and bone). Enthesopathy, a disorder involving the attachment of tendon or ligament, represents one-fourth of tendon diseases and is a difficult disorder to treat. Tendon disorders, which include enthesopathy, represent a considerable socioeconomic...

Published: 5/9/2024 | Inventor(s): Xu Cao

Keywords(s): Disease Indication, Joint Disorders, Single, Skeletal Disorders, Targeted Therapy, Therapeutic Matter, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Musculoskeletal, Clinical and Disease Specializations > Rheumatology, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Targets

Navigated Arthroscopic Treatment of Pincer-type Femoroacetabular Impingement with Precise 3D Planning

C11831: Hip Surgery Planning, Guidance, and Assessment SystemNovelty: A new method to perform arthroscopic hip surgeries with improved accuracy.Value Proposition: Femoroacetabular impingement (FAI) is characterized by poor interaction between femur and acetabulum that limits range of hip motion and can lead to early osteoarthritis for young and active...

Published: 5/9/2024 | Inventor(s): Mehran Armand, Ryan Murphy, Yoshito Otake, Marc Hungerford

Keywords(s): Disease Indication, Interventional and Surgical Systems, Joint Disorders, Surgical Navigation

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Rheumatology, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices

Methods, System, and Medium for Associating Rheumatoid Arthritis Subjects with Cardiovascular Disease

C11085: A Device Associating Rheumatoid Arthritis Subjects with Cardiovascular DiseaseNovelty: a computer implemented method for determining whether a rheumatoid arthritis patient is at risk for developing cardiovascular diseaseValue Proposition: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by progressive joint...

Published: 5/9/2024 | Inventor(s): Peter Alaupovic, Nicholas Knowlton, Adam Payne, Michael Centola, Joan Bathon, Jon Giles

Keywords(s): Arthritis, Assay, Autoimmune Diseases, Clinical Diagnostics, Computer and Network Systems, Computer Software, Diagnostic Tool, Disease Indication, In Vitro Diagnostics (Old), Inflammatory Disorders, Joint Disorders, Measurement Tool, Rheumatoid Arthritis

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Autoimmunity, Clinical and Disease Specializations > Rheumatology > Arthritis, Clinical and Disease Specializations > Rheumatology > Rheumatoid Arthritis, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Technology Classifications > Research Tools, Clinical and Disease Specializations > Rheumatology, Clinical and Disease Specializations > Immunology