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12612 B6.129-Gria1/J; 12613 B6.129-Gria1/J; 12614 B6.129-Gria1/J; 12615 B6.129-Gria2/J; 12616 B6.129-Gria3/J; 12617 B6.129-Gria3tm2R1h/J; 12618 B6.129-Gria4/J; 12619 B6.129-Gria4tm1R1h/J

C11079: Transgenic Gria mouse strains.Value Proposition: Transgenic Gria mouse strains: • 12612 B6.129-Grial/J • 12613 B6.129-Grial/J • 12614 B6.129-Grial/J • 12615 B6.129-Gria2/J • 12616 B6.129-Gria3/J • 12617 B6.129-Gria3tm2Rlh/J • 12618 B6.129-Gria4/J • 12619 B6.129-Gria4tmlRlh/J Published...

Published: 3/13/2025 | Inventor(s): Richard Huganir

Keywords(s): Addiction, Basic Research Biomarker, Cell Lines, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, In Vivo Research Tool, Knock In Mouse Model, Metabolic Disorders, Mouse Cell Lines, Mouse Model, Obesity

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Obesity

Treatment of Drug Abuse by Preventing GAPDH Nitrosylation

C12097: Novel Treatment for Cocaine Drug AbuseNovelty: A novel therapeutic strategy for cocaine abuse using known compounds.Value Proposition: Cocaine is a powerful addictive stimulant that causes psychological dependence and brain damage. Currently there are no FDA-approved drug for cocaine addiction and overdose, even though it is one of the most...

Published: 3/13/2025 | Inventor(s): Solomon Snyder, Risheng Xu, Nilkantha Sen

Keywords(s): Addiction, Biomarker, CNS and Neurological Disorders, Disease Indication, Mechanism of Action Biomarker, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Psychiatry > Addiction, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Psychiatry, Technology Classifications > Therapeutic Modalities