Search Results - angelo+demarzo

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5-hydroxymethylcytosine in Human Cancers

C11663: 5hmC: A Novel Marker for Cancer DetectionNovelty: The invention is a novel marker that can be detected in cancers using immunohistochemical (IHC) staining methods.Value Proposition: Cancers are often diagnosed in advanced stages, jeopardizing cancer patients’ chance to survive. This technique can detect different types of solid cancers...

Published: 3/12/2026 | Inventor(s): William Nelson, Angelo Demarzo, Alcides Chaux, Srinivasan Yegnasubramanian, Michael Haffner

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics

COMPARE-MS: A Novel Technique for Rapid, Sensitive, And Accurate Detection of DNA Methylation

C04871: COMPARE-MS: A Novel Technique for Rapid, Sensitive, And Accurate Detection of DNA MethylationTechnical Details: Hypermethylation of CpG island (CGI) sequences is a nearly universal somatic genome alteration in cancer. The rapid and sensitive detection of DNA hypermethylation can aid in cancer diagnosis and risk stratification but its detection...

Published: 3/12/2026 | Inventor(s): Xiaohui Lin, Srinivasan Yegnasubramanian, Angelo Demarzo, William Nelson

Keywords(s): Assay, Cancers, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics, In Vitro Research Tool, Target-based Screening Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Technology Classifications > Research Tools

Antibody to Human DNA Methyltransferase 1

C04328: Antibody to Human DNA Methyltransferase 1 Technical Details: We successfully prepared a polyclonal rabbit antibody to a peptide derived from the N-terminus of human DNMT1 (the sub-contractor was provided with the peptide sequence, synthesized the peptide, injected rabbits, and collected the immune sera; we characterized the antibodies and...

Published: 3/12/2026 | Inventor(s): Angelo Demarzo, William Nelson

Keywords(s): Antibodies, Basic Research Biomarker, Discovery/Research Tools, Peptides, Polyclonal Antibodies, Recombinant Proteins, Research Reagent

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Proteins, Ligands & Receptors