Search Results - clinical+and+disease+specializations+%3e+cardiovascular+%3e+myocardial+infarction

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Non-invasive Method to Localize Regions Susceptible to Reentry Using 3D Computational Modelling and Reentry Vulnerability Index Mapping

Unmet NeedLife threatening ventricular tachycardia (VT) is a precursor of sudden cardiac death. VT may occur in patients with weakened heart muscle such as in the case of myocardiopathy and/or chronic myocardial infarction (MI). Radiofrequency catheter ablation is applied to regions of conduction delay to treat and or prevent the recurrence of these...

Published: 6/28/2024 | Inventor(s): Natalia Trayanova, Ryan O'Hara, Ruben Coronel, Pouya Jelvehgaran

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular > Myocardial Infarction, Clinical and Disease Specializations > Cardiovascular > Ventricular Tachycardia, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Clinical Management

A Computational Flow Dynamics Based Method for Estimating Thromboembolic Risk in Patients with Myocardial Infarction

We present a unique method for quantitative assessment and estimation of thromboembolic risk in patients recovering from myocardial infarction. The method takes cardiac imaging data (CT, echo, CMR) from a patient and constructs a time]dependent geometric model of the left]ventricle (LV) from this data. This model is then subjected to computational fluid...

Published: 6/27/2024 | Inventor(s): Richard George, Jung Hee Seo, Rajat Mittal

Keywords(s): Cardiovascular Diseases, Clinical Diagnostics, Computer Systems Based on Mathematical Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Diagnostic Tool, Disease Indication, Image Processing Software, Image Reconstruction Software, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Measurement Tool, Myocardial Infarction, Myocardial Infarction (MI), Physics, X-ray Computed Tomography (CT), X-Ray Computed Tomography (CT)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Myocardial Infarction, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Medical Devices > Imaging, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices

Implantable Bioreactor with a Non-Static Cell Pouch

UNMET NEED Heart failure after myocardial infarction (MI) is a common and morbid condition that affects millions worldwide. While there are multiple therapies that help the heart adapt and compensate for the damage incurred in an MI, there remains no method by which injured heart muscle may be repaired or replaced. Stem cell therapy shows great promise...

Published: 6/27/2024 | Inventor(s): Chao-Wei Hwang, Gary Gerstenblith, Peter Johnston, Robert Weiss, Gordon Tomaselli, Steven Schulman

Keywords(s): Cardiovascular Diseases, Cell Therapy, Disease Indication, Implanted Device, Implants, Myocardial Infarction (MI), Single, Therapeutic Devices, Therapeutic Matter, Therapeutic Substance Synthesis Method, Therapeutics, Therapy Type, Tissue Engineering/Regenerative Devices

Category(s): Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Cardiovascular > Myocardial Infarction

Biomarkers of Myocardial Injury

C12557: CARDIAC INJURY DIAGNOSTIC BIOMARKERSInvention novelty: Biomarkers identified for accurate and differential diagnosis and prognosis of cardiac injury and associated delayed adverse event related risksValue Proposition: Currently, various tests have been used to detect myocardial events. The clinically available tests include assays for measuring...

Published: 6/27/2024 | Inventor(s): Qin Fu, Jennifer Van Eyk, Vidya Venkatraman

Keywords(s): Biomarker, Cardiovascular Diseases, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Myocardial Infarction, Myocardial Infarction (MI)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Myocardial Infarction, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Diagnostics

C11620: Novel Treatment for Heart Attack

Novelty: The outlined invention features the novel therapeutic implications of a drug in preventing cardiac cell loss that occurs in myocardium infraction.Value Proposition: The technology describes the application of a drug to treat a major public health problem for which there is no current medical treatment option. The main features of the invention...

Published: 6/27/2024 | Inventor(s): Kotohiko Kimura, Ru Chih Huang

Keywords(s): Antagonists/Inhibitors, Cardiovascular Diseases, Disease Indication, Myocardial Infarction, Myocardial Infarction (MI), Non-novel, Predicted Novelty, Repurposed, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Myocardial Infarction, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Therapeutic Modalities

Biomarkers of Myocardial Ischemia

C10179: Biomarkers of Myocardial IschemiaValue Proposition: Detection of ischemic myocardium as an early indication of cardiac injury allowing early detection of myocardial infarction and cell death.Technical Details: Coronary heart disease is the most common single cause of death in the western world representing ~20% of all deaths. This is equivalent...

Published: 6/27/2024 | Inventor(s): Qin Fu, Simon Sheng, Jennifer Van Eyk

Keywords(s): Biomarker, Cardiovascular Diseases, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Myocardial Infarction, Myocardial Infarction (MI)

Apolipoprotein C-1 Induced Apoptosis

C04159: Apolipoprotein C-1 Induced Apoptosis Technical Details: Apolipoprotein C-I, a small basic protein in human blood, induces apoptosis in cultured human arterial smooth muscle cells through the neutral sphingomyelin (N-SMase) pathway, and the subsequent second messenger steps. An inhibitor of N-SMase abrogates this effect.Looking for Partners:...

Published: 6/27/2024 | Inventor(s): Peter Kwiterovich, Subroto Chatterjee

Keywords(s): Basic Research Biomarker, Cardiovascular Diseases, Cell Signaling, Discovery/Research Tools, Disease Indication, Inhibitors, Myocardial Infarction (MI), Research Reagent

Category(s): Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools, Clinical and Disease Specializations > Cardiovascular > Myocardial Infarction