Search Results - dwight+bergles

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NG2-cDTa mice

C11678: Transgenic Mouse Line with Inducible Diphtheria Toxin GeneNovelty: A novel line of transgenic mice expressing stable inducible diphtheria toxin gene under the control of an NG-2 promoter. This mouse line can be used in neuroscience studies to induce a model state of chronic demyelination.Value Proposition: Neuronal cell studies are an important...

Published: 6/27/2024 | Inventor(s): Shin Kang, Dwight Bergles

Keywords(s): Amyotrophic Lateral Sclerosis, Amyotrophic Laterial Sclerosis (ALS), Basic Research Biomarker, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vivo Research Tool, Knock In Mouse Model, Motor Neuron Diseases, Mouse Model, Mouse Model Xenograft, Neurodegeneration

R26-lsl-GCaMP3 mice

C11677: Transgenic Mouse Line for In Vivo Calcium Ion MonitoringNovelty: Unique transgenic mouse model comprising genetically encoded calcium indicator, GCaMP3, to monitor calcium signaling in vivo.Value Proposition: Commonly used calcium indicator dyes lack specificity and may produce error in measuring intracellular calcium. This invention is a transgenic...

Published: 6/27/2024 | Inventor(s): Amit Agarwal, Dwight Bergles

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools

PDGFaR-CreER mice

C11676: PDGF Receptor Transgenic Mouse Line with Inducible Cre RecombinaseNovelty: Transgenic mouse line containing inducible Cre recombinase expressed under the control of platelet derived growth factor alpha receptor (PDGF\R) promoter. This PDGFR-CreER mouse model is a useful resource for studying cell specific genetic regulation of oligodendrocytes...

Published: 6/27/2024 | Inventor(s): Shin Kang, Dwight Bergles

Keywords(s): Basic Research Biomarker, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vivo Research Tool, Knock In Mouse Model, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Clinical and Disease Specializations > Neurology

NG2-lck_EGFP Mice

C11675: NG2-lck-EGFP Transgenic Mouse LineNovelty: Transgenic mouse line expressing the eGFP reporter that is controlled by an NG2 promoter. This mouse model is a useful resource for in vivo as well as in vitro study of neuronal development and function.Value Proposition: Neuroglial cells like pericytes and oligodendrocytes express NG-2 proteoglycans...

Published: 6/27/2024 | Inventor(s): Shin Kang, Dwight Bergles

Keywords(s): Discovery/Research Tools, In Vivo Research Tool, Mouse Model

Category(s): Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Diagnostics, Technology Classifications > Research Tools