Search Results - huaibin+cai

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Beta-Secretase (BACE1) Polyclonal Antisera

C03929: Beta-Secretase (BACE1) Polyclonal Antisera Technical Details: To facilitate our understanding of the physiological role of BACE1 and its involvement in the generation of the Alzheimer?s disease (AD) Ab peptides, we generated a rabbit polyclonal antibody against BACE1. Our BACE1 antisera will be useful in the BACE1 levels and expression patterns...

Published: 6/26/2025 | Inventor(s): Huaibin Cai, Donald Price, Philip Wong

Keywords(s): Alzheimer's Disease, Antibodies, Biologics, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, Geriatric Conditions, Neurodegeneration, Proteomics/Immunoassays, Proteomics/Immunoassays Antiserum, Research Reagent, Therapeutic Matter, Therapeutic Substance, Therapeutics, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Geriatrics, Clinical and Disease Specializations > Neurology > Alzheimer's Disease, Clinical and Disease Specializations > Neurology > Neurodegeneration, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Assays, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools

Beta-Secretase (BACE1) Knockout Fibroblast Cells

C03882: Beta-Secretase (BACE1) Knockout Fibroblast Cells Technical Details: We have developed BACE1 knockout cells to further facilitate our understanding of physiological consequences of the lack of BACE1 in cells. We have established BACE1 knockout immortalized cell lines by transforming the primary fibroblasts derived from BACE1 knockout mice. Looking...

Published: 6/26/2025 | Inventor(s): Donald Price, Huaibin Cai, Philip Wong

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools

Beta - Secretase (BACE1) Knockout Mice

C03774: Beta - Secretase (BACE1) Knockout Mice Technical Details: Two beta-secretases termed BACE1 and BACE2 have been shown to generate the Alzheimer's disease Abeta peptides. To examine the physiological roles of BACE1 and to determine whether BACE1 is the major beta-secretase in neurons, Johns Hopkins University researchers have created mice...

Published: 6/26/2025 | Inventor(s): Huaibin Cai, Donald Price, Philip Wong

Keywords(s): Alzheimer's Disease, Basic Research Biomarker, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model, Neurodegeneration

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Geriatrics, Clinical and Disease Specializations > Neurology > Alzheimer's Disease, Clinical and Disease Specializations > Neurology > Neurodegeneration, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Research Tools > Animal Models, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools