Search Results - ronald+schnaar

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Identification of a Specific Ligand for Siglec-8

C04430: Novel Carbohydrate Based Therapeutic for Allergic, Asthmatic, and Other Inflammatory DisordersNovelty: A Sialic acid immunoglobulin-like lectin-8 (Siglec-8) carbohydrate based ligand has been identified which provides a platform for development of effective therapies for inflammation caused by eosinophil, basophil and mast cell over activity.Value...

Published: 3/13/2025 | Inventor(s): Ronald Schnaar, Bruce Bochner

Keywords(s): Disease Indication, Inflammatory Disorders, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Inflammation, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities

Eight Anti-ganglioside Monoclonal Antibodies

C04184: Eight Anti-ganglioside Monoclonal Antibodies Technical Details: Monoclonal antibodies to major brain cell surface antigens involved in axon-myelin stability, nerve regeneration, and control of nerve cell signaling.Looking for Partners: Diagnostic analysis, neuropathic localization

Published: 3/13/2025 | Inventor(s): Kazim Sheikh, Ronald Schnaar

Keywords(s): Antibodies, Biologics, Discovery/Research Tools, Disease Indication, Monoclonal Antibodies, Nerve Disorders and Injury, Nerve Injury, Research Reagent, Therapeutic Matter, Therapeutic Substance, Therapeutics, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Research Tools, Technology Classifications > Therapeutic Modalities

Monoclonal Antibodies to Gangliosides Raised in Ganglioside-Deficient Knockout Mice

C03663: Monoclonal Antibodies to Gangliosides Raised in Ganglioside-Deficient Knockout Mice Technical Details: Knock-out mice lacking complex gangliosides were found to be improved hosts for raising high affinity, high titer monoclonal IgG anti-ganglioside antibodies. Gangliosides are major cell surface determinants in the vertebrate nervous system....

Published: 3/13/2025 | Inventor(s): Kazim Sheikh, Ronald Schnaar, Michael Lunn

Keywords(s): Antibodies, Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Knock Out Mouse Model, Monoclonal Antibodies, Mouse Model, Research Reagent

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools