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A Novel methodology for arrhythmia risk stratification by assessing qt interval instability

Clinical studies have demonstrated that beat-to-beat instability in QT interval, which is the global manifestation of instability in ventricular repolarization dynamics, predicts propensity to arrhythmias. However, a robust methodology to assess QT interval instability and thus predict propensity to arrhythmia in a patient-specific manner is currently...

Published: 10/23/2025 | Inventor(s): Xiaozhong Chen, Natalia Trayanova

Keywords(s): Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Physics

Category(s): Technology Classifications > Computers, Electronics & Software

Chemical Control of Trk Signaling in Mice

Value Proposition· Selective and reversible control: Enables specific inhibition of individual Trk receptors (TrkA, TrkB, TrkC) without affecting other cellular processes or wild-type neurons· Temporal precision: Allows researchers to control exactly when neurotrophin signaling is blocked through oral drug administration, enabling studies...

Published: 10/23/2025 | Inventor(s): David Ginty, Xi Chen

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, Growth Factors, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model, Recombinant Proteins, Research Reagent

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools