Search Results - yuchen+jiao

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Compositions and Biomarkers for Human Cancer and Methods of Use

Novel biomarkers for the detection and prognosis of several cancersJHU REF: C12506 Invention novelty: This invention has discovered high frequency mutations in the telomerase reverse transcriptase (TERT) promoter of certain cancers. Value Proposition: Early detection is usually critical for the successful treatment of cancer, therefore there is...

Published: 9/26/2024 | Inventor(s): Bert Vogelstein, Kenneth Kinzler, Nickolas Papadopoulos, Chetan Bettegowda, Yuchen Jiao, Darell Bigner, Hai Yan, Zachary Reitman, Patrick Killela

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Mechanism-of-action Biomarker, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > Prognostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Technology Classifications > Therapeutic Modalities

Mutations of ATRX in Brain Tumors

C11618: Novel Molecular Diagnostic for Aggressive Brain TumorsNovelty: A genetic mutation in the ATRX or DAXX genes previously unknown for its presence in various aggressive brain tumors was discovered and thereby provides an attractive diagnostic opportunity.Value Proposition: Previously unreported changes in ATRX or DAXX gene’s amino acid sequence...

Published: 9/26/2024 | Inventor(s): Luis Diaz, Alan Meeker, Hai Yan, Nickolas Papadopoulos, Darell Bigner, Yuchen Jiao, Ralph Hruban, Kenneth Kinzler, Bert Vogelstein

Keywords(s): Basic Research Biomarker, Biomarker, Brain Cancer, Cancer Cells, Cancers, Cell Model, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics (Old), In Vitro Research Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Oncology > Brain Cancer, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Diagnostic Biomarkers

DAXX/A TRX genes provide prognostic information in cancers

C11331: Methods and Biomarkers for the detection of Pancreatic Neuroendrocrine TumorsValue Proposition: • Mutations useful to accurately diagnose a patient with pancreatic neuroendocrine tumor • Novel prognostic indicators that predict clinical outcome • Genetic mutations identified that are useful to select and implement an appropriate...

Published: 9/26/2024 | Inventor(s): Nickolas Papadopoulos, Victor Velculescu, Luis Diaz, Yuchen Jiao, Kenneth Kinzler, Ralph Hruban, Bert Vogelstein

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Mechanism-of-action Biomarker, Pancreatic Cancer, Prognostic Biomarker, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Pancreatic Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Prognostics Biomarkers, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities