Search Results - erika+darrah

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Antibodies that Enhance PAD4 Activity for the Study of Autoimmune Diseases

Value Proposition· Enhanced Research Capabilities: Provides five distinct human monoclonal antibodies that enhance PAD4 activity for in vitro and in vivo experimental assays, enabling researchers to study PAD4's function in autoimmune diseases such as rheumatoid arthritis.· Scalable Production: Utilizes commercially available immortalized...

Published: 7/24/2026 | Inventor(s): Felipe Andrade, Jing Shi, Antony Rosen, Erika Darrah

Keywords(s): Antibodies, Autoimmune Diseases, Basic Research Biomarker, Discovery/Research Tools, Disease Indication, Inflammatory Disorders, Monoclonal Antibodies, Research Reagent

Category(s): Clinical and Disease Specializations > Autoimmunity, Technology Classifications > Diagnostics, Technology Classifications > Research Tools > Antibodies

Recombinant anti-PAD4 antibodies as a treatment for lung fibrosis

Value PropositionSelective monoclonal antibody therapy to treat lung fibrosis.Directly targets immune cells to promote a pro-inflammatory pathway that reduces fibrosis.High serum levels are associated with less severe lung disease, decreased fibrosis, and improved survival in a subset of rheumatoid arthritis patients.Broadly applicable to other diseases...

Published: 7/24/2026 | Inventor(s): Erika Darrah, Felipe Andrade, Kristen Demoruelle, Elizabeth Redente

Keywords(s):

Category(s): Clinical and Disease Specializations > Fibrosis, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications, Technology Classifications > Therapeutic Modalities

Autoimmunity-based Peptides as Cancer Vaccines

Autoimmunity-based Peptides as Cancer Vaccines JHU REF: C12807 Invention novelty: This technology uses autoantigen-derived peptides as novel immunotherapy to prevent and treat cancer. Value Proposition: Today, millions of people are living with cancer or have had cancer. Despite significant advances in cancer diagnosis and treatment over the...

Published: 7/23/2026 | Inventor(s): Erika Darrah, Christine Joseph, Kenneth Kinzler, Livia Casciola-Rosen, Nickolas Papadopoulos, Ami Shah, Antony Rosen, Bert Vogelstein

Keywords(s): Antigens, Biologics, Cancers, Disease Indication, Immunotherapy, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Vaccine

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Vaccines