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ABSTRACTAtox1 is a 7.6 kDa cytosolic protein that plays an important role in human copper metabolism. The recombinant intein-fusion of Atox1 was expressed in E.coli, intein tag was cleaved during purification and purified Atox1 was used for immunization of rabbits. Serum containing anti-Atox1 antibodies was tested using mouse liver homogenates and purified...

Published: 6/12/2026 | Inventor(s): Svetlana Lutsenko, Yuta Hatori

Keywords(s): Antibodies, Biologics, Discovery/Research Tools, In Vitro Research Tool, In Vivo Research Tool, Rabbit Model, Research Instrument, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Antibodies

Guinea Pig-passaged H37Rv rel Mtb Mutant, rel Complement Strain, rel Tetracycline-inducible Knock-in Strain, rel Tetracycline-inducible Knock-down Strain

C11518: Transgenic rel Tubercle Bacilli for Anti-Tuberculosis Drug ScreeningNovelty: Transgenic guinea pig-passaged tubercle bacilli with modified rel expression levels useful for the identification of novel anti-tuberculosis therapeutics.Value Proposition: To date, tuberculosis (TB) infections are often unrecognized due to the ability of tubercle bacilli...

Published: 6/12/2026 | Inventor(s): Petros Karakousis

Keywords(s): Bacterial Infections, Basic Research Biomarker, Discovery/Research Tools, Disease Indication, In Vivo Research Tool, Infectious Diseases, Knock Out Rabbit Model, Rabbit Model, Tuberculosis (TB)

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis (TB)