Search Results - wound+healing

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Dextran Hydrogel Scaffolds Enhance Angiogenic Responses and Promote Complete Skin Regeneration During Burn Wound Healing

Unmet Need:Third-degree burns involve damage to both the epidermal and dermal layers and may also entail damage to underlying muscles, bones, and tendons. Such burns heal with thick scars, which result in contractures that distort the surrounding tissue. Deep third-degree burns usually require skin grafting to achieve wound closure, but the cosmetic...

Published: 5/9/2024 | Inventor(s): Guoming Sun, Xianjie Zhang, John Harmon, Sharon Gerecht

Keywords(s): Disease Indication, Drug Delivery Vehicle, Hydrogel, Therapeutic Matter, Therapeutics, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities

Use of Combination Retinoic Acid and dsRNA Products for Skin Rejuvenation

Unmet NeedGlobally, the anti-aging cosmetic treatment market is projected to grow to $57.5B dollars in 2020. Currently, one of the leading the leading topical ingredients in anti-aging creams for wrinkle reduction is retinoids, which are derivatives of vitamin A. Retinoic acid, the active metabolite of retinoids, has been shown to help repair sun damaged...

Published: 5/9/2024 | Inventor(s): Luis Garza, Dongwon Kim

Keywords(s): Biologics, Chemotherapy/Immunotherapy, Combination, Disease Indication, Nucleic Acid, Skin Disorders, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Wound Healing

Category(s): Technology Classifications > Therapeutic Modalities

Multiphase Transitioning Peptride Hydrogel for Use in Vascular Anastamosis

Unmet NeedThe formation of vascular anastomosis, the joining of two blood vessels, is a fairly common procedure utilized by many surgeons. All vascular bypass operations and solid organ transplants require anastomoses. However, as the vessels being anastomosed become smaller or less firm, surgeons have exponentially increasing rates of failure. In...

Published: 5/9/2024 | Inventor(s): Daniel Smith, Johanna Grahammer, Joel Schneider, Gerald Brandacher, Gabriel Brat

Keywords(s): Disease Indication, Implanted Device, Implants, Therapeutic Devices, Therapeutics, Tissue Engineering/Regenerative Devices, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices

Cancer in Angiogenesis

Unmet NeedIn the United States alone, almost 8.5 million people suffer from peripheral artery disease (PAD). The market for PAD and Peripheral Vascular Disease (PVD) is expected to reach $378.53 million with a CAGR of 7.06% by 2024. Therapeutic angiogenesis are therapies aimed at growing new vessels into compromised tissue. Wound healing, PAD, and coronary...

Published: 5/9/2024 | Inventor(s): Andrew Schulick

Keywords(s): Biologics, Cardiovascular Diseases, Cell Model, Coronary Heart Disease, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Peripheral Artery Disease, Stem Cells, Therapeutic Matter, Therapeutic Substance, Therapeutic Substance Synthesis Method, Therapeutics, Whole cell, Wound Healing

Category(s): Technology Classifications > Therapeutic Modalities > Stem Cells, Clinical and Disease Specializations > Wound Healing, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Research Tools > Stem Cells

Wound Healing Compositions Comprising Biocompatible Cellulose Hydrogel Membranes and Methods of Use Thereof

Unmet NeedCorneal lacerations are a common type of eye injury. These can occur in varying degrees of severity, and in many cases the wound is non-self-sealing. This type of injury requires significant intervention including sutures and, in some cases, many layers of grafts. During the course of treatment patients are required to wear bandages that can...

Published: 5/9/2024 | Inventor(s): Jennifer Elisseeff, Daniel Mulreany, Qiongyu Guo, Morgana Trexler, Jennifer Breidenich, Jeffrey Maranchi, Iossif Strehin, Jemin Chae, Oliver Schein, Russel Mccally, Jenna Graham, Julia Patrone, Marcia Patchan, Xiomara Calderon-Colon

Keywords(s): Disease Indication, Implanted Device, Implants, Therapeutic Devices, Therapeutics, Tissue Engineering/Regenerative Devices, Wound Healing

Angiotensin Type 1 Receptor Autoantibody in Wound Healing

Unmet Need:Chronic wounds are among the most common, painful, debilitating and costly conditions in diabetics and in older adults, and are an important portal for bacterial infections that often lead to amputations, sepsis and mortality. In diabetic and aging skin, chronic inflammation commonly accompanies poor wound healing and increases the risk for...

Published: 5/9/2024 | Inventor(s): Peter Abadir, Jeremy Walston, Alka Jain, Neal Fedarko

Keywords(s): Biomarker, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Prognostic Biomarker, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Prognostics Biomarkers, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Technology Classifications > Therapeutic Modalities

Outgassing of Hyperbarically Loaded Polymeric Materials for Biomedical Applications

Unmet NeedTherapeutic gas delivery remains one of the greatest challenges in tissue engineering. Consequently many technologies and approaches have been developed but all lackeffective ways to deliver sufficient therapeutic gas, such as oxygen, to targeted regions within deeper tissue. This invention introduces a means of delivering therapeutic gases...

Published: 5/9/2024 | Inventor(s): Warren Grayson, Colin Cook

Keywords(s): Disease Indication, Drug Delivery Vehicle, Implantation Method, Implanted Device, Implants, Therapeutic Devices, Therapeutic Matter, Therapeutics, Tissue Engineering/Regenerative Devices, Wound Healing

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Wound Healing

Hypoxia-inducible Hydrogels

Hypoxia, low oxygen tension, plays a pivotal role during development, regeneration, and cancer. However, nobody has stimulated hypoxia in a 3D microenvironment. Here, we developed a fundamental technology to create hydrogel materials that can serve as 3D hypoxic microenvironments. The HI hydrogels are formed via oxygen consumption in a laccase-mediated...

Published: 5/9/2024 | Inventor(s): Kyung Min Park, Sharon Gerecht

Keywords(s): Bioreactor-based Manufacturing, Disease Indication, Implanted Device, Implants, Industrial Manufacturing, Manufacturing Method, Therapeutic Devices, Therapeutics, Tissue Engineering/Regenerative Devices, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Industrial Tech > Industrial Manufacturing, Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Industrial Tech, Technology Classifications > Medical Devices, Technology Classifications > Engineering Tech > Industrial Manufacturing

dsRNA Analogues to Promote Skin Regeneration

C12197: RNA Mediated Skin RegenerationInvention novelty: This invention is a method to increase skin regeneration and wound healing. It relies on activation of the innate immune response involving Toll-like receptor 3 (TLR3). Value Proposition: Current approaches to wound healing and skin regeneration are limited in that they do not lead to scar free...

Published: 5/9/2024 | Inventor(s): Amanda Nelson, Luis Garza

Keywords(s): Biologics, Disease Indication, Follicular Neogenesis, Follicular neogenesis, Hair Disorders, Nucleic Acid, Therapeutic Matter, Therapeutic Substance, Therapeutics, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Dermatology > Follicular Neogenesis, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Gene Therapies, Clinical and Disease Specializations > Dermatology, Technology Classifications > Therapeutic Modalities

Methods to Accelerate Healing of Injured Tissues via Stem Cells in Nanofiber Patches

C12353: Stem Cell Developed Patches for Accelerated AngiogenesisNovelty: This technology describes compositions and methods of use of certain patches, with infused stem cells and/or derived growth factors, used for accelerated healing of tissue injuries.Value Proposition: Existing therapeutic angiogenesis techniques that employ individual growth factors...

Published: 5/9/2024 | Inventor(s): Xiomara Calderon-Colon, Zhiyong Xia, Chao-Wei Hwang, Peter Johnston, Virginia Bogdan

Keywords(s): Disease Indication, Implanted Device, Implants, Therapeutic Devices, Therapeutics, Tissue Engineering/Regenerative Devices, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Stem Cells, Technology Classifications > Medical Devices

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