Search Results - alberto+bardelli

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Mutational Analysis of the Serine-threonine Kinome in Colorectal Cancers

C04724: Mutational Analysis of the Serine-threonine Kinome in Colorectal Cancers Technical Details: The invention describes novel mutations in serine-threonine kinase genes within the Phosphatidylinositol-3-OH Kinase (PI(3)K) pathway in patients with colorectal cancer. Details are described in the paper by Parsons et al., 2005 (see below). Looking...

Published: 3/13/2025 | Inventor(s): Alberto Bardelli, Christoph Lengauer, Yardena Samuels, Donald Parsons, Tian-Li Wang, Kenneth Kinzler, Victor Velculescu, Bert Vogelstein

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Colorectal Cancer, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

Carcinogen-specific Induction of Genetic Instability

C03921: Carcinogen-specific Induction of Genetic Instability Technical Details: The researchers created two H3 colorectal cancer cell lines. One cell line has chromosomal instability (CIN) and resistance to 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP). The other cell line has microsatelite instability (MIN) and resistance to methylating...

Published: 3/13/2025 | Inventor(s): Alberto Bardelli, Kenneth Kinzler, Christoph Lengauer, Bert Vogelstein

Keywords(s): Basic Research Biomarker, Cancers, Cell Lines, Colorectal Cancer, Discovery/Research Tools, Disease Indication, Gastric Cancer, Human Cell Lines, In Vitro Research Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools