Search Results - gastric+cancer

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Global DNA Hypomethylation as Biomarker for Clinical Detection, Inflammation Severity, and Disease Progression in Gastric Cancer

C11444: Novel Biomarker for Diagnosis of Gastric CancerNovelty: The reported technology identifies a novel biomarker for clinical detection, inflammation severity, and disease progression in gastric cancer.Value Proposition: The technology outlined is a diagnostic technique to detect a biomarker known to play a major role in gastric carcinogenesis....

Published: 3/13/2025 | Inventor(s): David Sidransky, Rafael Guerrero-Preston

Keywords(s): Assay, Biomarker, Cancers, Clinical Diagnostics, Disease Indication, Gastric Cancer, In Vitro Diagnostics, Prognostic Biomarker, Risk Stratification

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology > Gastric Cancer

Detection and Elimination of Colonic Co-colonization with Enterotoxigenic Bacteroides Fragilis and pks+ Escherichia Coli in the Prevention of Colon Cancer

Unmet NeedFamilial adenomatous polyposis (FAP) is a hereditary condition caused by a mutation in the APC tumor suppressor gene, with a reported incidence of 1 in 7,000 to 1 in 22,000 individuals. Patients with FAP develop thousands of colorectal polyps that will eventually become malignant, resulting in colorectal cancer later in life. The onset and...

Published: 3/14/2025 | Inventor(s): Cynthia Sears, Christine Craig, Drew Pardoll

Keywords(s): Assay, Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Discovery/Research Tools, Disease Indication, Gastric Cancer, In Vitro Diagnostics (Old), In Vitro Research Tool, Research Instrument

Category(s): Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays

BARH-like Gene 1 (BARX1) in Gastric Carcinogenesis

C11718: Novel Epigenetic Diagnostic Biomarker for Gastric CancerNovelty: A novel epigenetic biomarker for gastric cancer to enable earlier diagnosis and subsequent intervention.Value Proposition: Currently gastric cancer is diagnosed by tissue biopsies, which are invasive and can be inaccurate, often resulting in delayed diagnosis. This invention identified...

Published: 3/13/2025 | Inventor(s): Stephen Meltzer, Rachana Agarwal

Keywords(s): Biomarker, Cancer Cells, Cancers, Cell Model, Clinical Diagnostics, Diagnostic Biomarker, Discovery/Research Tools, Disease Indication, Gastric Cancer, In Vitro Diagnostics, In Vitro Research Tool, Prognostic Biomarker, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Gastric Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools, Technology Classifications > Diagnostics > Prognostic Biomarkers

An Endoscopic Device and Method to Retrieve Tetherless Microtools

C11519: Improved Colon Biopsy Devices: Tetherless Microtools and Magnetic Deployment/ Retrieval EndoscopeNovelty: The device and method is used to retrieve tissue with minimally invasive and collects large numbers of samples.Value Proposition: Current colon biopsy methods include collection of many, relatively large samples from multiple areas in the...

Published: 3/13/2025 | Inventor(s): David Gracias, Anthony Kalloo, Mouen Khashab, Florin Selaru

Keywords(s): Cancers, Clinical Diagnostics, Colorectal Cancer, Discovery/Research Tools, Disease Indication, Gastric Cancer, In Vitro Diagnostics, In Vitro Research Tool, Interventional and Surgical Systems, Pathology Tools, Sample Collection Method, Surgical Instruments

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Gastric Cancer, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Colorectal Cancer

Carcinogen-specific Induction of Genetic Instability

C03921: Carcinogen-specific Induction of Genetic Instability Technical Details: The researchers created two H3 colorectal cancer cell lines. One cell line has chromosomal instability (CIN) and resistance to 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP). The other cell line has microsatelite instability (MIN) and resistance to methylating...

Published: 3/13/2025 | Inventor(s): Alberto Bardelli, Kenneth Kinzler, Christoph Lengauer, Bert Vogelstein

Keywords(s): Basic Research Biomarker, Cancers, Cell Lines, Colorectal Cancer, Discovery/Research Tools, Disease Indication, Gastric Cancer, Human Cell Lines, In Vitro Research Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Oncology > Colorectal Cancer, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools