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Search Results - clinical+and+disease+specializations+%3e+infectious+diseases+%3e+hiv
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Self-Assembling Antiviral Prodrugs for Long-Acting Treatment of Chronic HIV Infections
Unmet Need / Invention Novelty: The need for long-acting HIV drugs arises from challenges such as pill burden, side effects, and stigma, which contribute to inconsistent use and reduced effectiveness. A long-acting antiretroviral formulation could enhance treatment adherence, reduce disease transmission, and better support populations facing barriers...
Published: 3/14/2025
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Inventor(s):
Honggang Cui
,
Charles Flexner
,
Maya Monroe
,
Han Wang
Keywords(s):
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Infectious Diseases
,
Technology Classifications > Therapeutic Modalities
,
Technology Classifications > Therapeutic Modalities > Peptides
,
Clinical and Disease Specializations > Infectious Diseases > HIV
,
Clinical and Disease Specializations > Infectious Diseases > HIV
/AIDS
,
Clinical and Disease Specializations > Infectious Diseases > Hepatitis B Virus
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Clinical and Disease Specializations > Infectious Diseases > Viral Infections
Inhibition of nSMase for the Treatment of Human Immunodeficiency Virus Infection
Unmet NeedHuman immunodeficiency virus (HIV) is a retrovirus that negatively impacts the immune system, leading to immunosuppression and increased susceptibility to secondary, opportunistic infections and some cancers. It is estimated that 36.7 million people worldwide are currently living with HIV. Presently, HIV has no cure and requires life-long...
Published: 3/13/2025
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Inventor(s):
Norman Haughey
,
Barbara Slusher
,
Camilo Rojas
Keywords(s):
Antagonists/Inhibitors
,
Disease Indication
,
HIV
,
Infectious Diseases
,
Small Molecules
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Technology Classifications > Therapeutic Modalities > Small Molecules
,
Clinical and Disease Specializations > Infectious Diseases > HIV
Antibodies associated with HIV control
Value Proposition· Target associated with viral load reduction identified from a large pool of study participants who had low level viremia· Potential to reduce disease severity in at-risk populations· Proactive approach to lower viral load in individuals who could become infected Unmet NeedHuman immunodeficiency virus (HIV) impacts millions...
Published: 3/14/2025
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Inventor(s):
Susan Eshleman
,
Harry Larman
,
Kai Kammers
,
Oliver Laeyendecker
,
Wendy Grant-McAuley
Keywords(s):
Category(s):
Clinical and Disease Specializations > Infectious Diseases > HIV
,
Clinical and Disease Specializations > Infectious Diseases > HIV
/AIDS
,
Technology Classifications > Therapeutic Modalities > Antibodies
,
Technology Classifications > Therapeutic Modalities > Therapeutic Antibodies
Monoclonal antibodies (and their Production) against HIV and SIV co-receptors: Chemokine receptors
C03243: Monoclonal antibodies (and their Production) against HIV and SIV co-receptors: Chemokine receptors Technical Details: These monoclonal antibodies are specific for the chemokine receptors CXCR4 and CCR5, which mediate entry of HIV and SIV into susceptible cells.
Published: 3/13/2025
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Inventor(s):
James Hildreth
Keywords(s):
Antibodies
,
Basic Research Biomarker
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Biologics
,
Discovery/Research Tools
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Disease Indication
,
HIV
,
Infectious Diseases
,
Monoclonal Antibodies
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Natural compounds
,
Non-novel
,
Predicted Novelty
,
Research Reagent
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Therapeutic Modalities > Antibodies
,
Technology Classifications > Therapeutic Modalities > Biologics
,
Technology Classifications > Research Tools
,
Technology Classifications > Therapeutic Modalities
,
Clinical and Disease Specializations > Infectious Diseases > HIV
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