Search Results - josh+lauring

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PIK3CA wild type and AKT1 E17K and PIK3CA H1047R knock-in MCF-7 cells

C12186: PIK3CA Wild Type and AKT1 E17K and PIK3CA H1047R Knock-in MCF-7 CellsNovelty: MCF-7 derivatives with different mutations in the phosphatidylinositol-3-kinase (PI3-kinase) pathway gene PIK3CA and AKT1.Value Proposition: MCF-7 is the most widely used human breast cancer cell line, and it serves as a valuable model for preclinical investigations...

Published: 1/22/2026 | Inventor(s): Ben Ho Park, Josh Lauring

Keywords(s): Breast Cancer, Cancer Cells, Cancers, Cell Lines, Cell Model, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools

AKT1 Knock in Cells

C10605: AKT1 Knock in Cells Value Proposition: JHU scientists have generated a cell line incorporating a single base pair mutation “knocked in” within the AKT1 oncogene, single allele, into the MCF-10A human breast epithelial cell line resulting in a heterozygous E17K amino acid change. Additionally, a control “knock in” wild type cell line was...

Published: 1/22/2026 | Inventor(s): Josh Lauring, Ben Ho Park

Keywords(s): Cell Lines, Cell Model, Discovery/Research Tools, Epithelial Cells, Human Cell Lines, In Vitro Research Tool, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools

MMSET Knock Out and Knock Down Multiple Myeloma Cells

C10575: MMSET Knock Out and Knock Down Multiple Myeloma Cells Value Proposition: • Effective knockout/knockdown Multiple Myeloma cells line for the study of t(4;14)(p16;q32), worst prognostic subgroup in Multiple Myeloma Patients. Technical Details: Multiple myeloma (MM) is an incurable hematologic malignancy characterized by recurrent chromosomal...

Published: 1/22/2026 | Inventor(s): Josh Lauring, Ben Ho Park

Keywords(s): Basic Research Biomarker, Blood Cancer, Cancer Cells, Cancers, Cell Model, Discovery/Research Tools, Disease Indication, Hematologic Malignancies, In Vitro Research Tool, Multiple Myeloma

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Hematology, Clinical and Disease Specializations > Oncology > Hematologic Malignancies, Clinical and Disease Specializations > Oncology > Multiple Myeloma, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Human Cell Lines