Search Results - mark+soloski

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Host Response Biomarker Panel for Diagnosis of Lyme Disease

Invention Novelty This diagnostic technology uses a panel of 20 biomarkers to diagnose Lyme disease with much higher sensitivity and accuracy than other currently existing methods. Lyme disease can be detected in peripheral blood samples from patients even at early hard-to-diagnose stages. These aspects of the invention make it indispensable for...

Published: 3/13/2025 | Inventor(s): John Aucott, Mark Soloski, Charles Chiu, Jerome Bouquet

Keywords(s): Biomarker, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Infectious Diseases, Lyme Disease

Category(s): Clinical and Disease Specializations > Immunology > Lyme Disease

Elevated CCL19 after Completion of Therapy for Acute Lyme Disease Identifies Patients at Risk for Development of Post-treatment Lyme Disease Syndrome Who Will Benefit from Further Antibiotic Therapy

Unmet Need: Lyme disease is the most common tick-borne disease in temperate regions that can lead to persistent and life-altering symptoms including arthritis and neurological dysfunction. Even when caught and treated early, approximately 10-20% of patients have persistent symptoms lasting 6+ months known as posttreatment Lyme disease syndrome (PTLDS)....

Published: 3/13/2025 | Inventor(s): John Aucott, Mark Soloski

Keywords(s): Bacterial Infections, Biomarker, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Infectious Diseases, Lyme Disease, Risk Stratification

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Lyme Disease, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases

Anti Qa-1 Monoclonal Antibodies

C03422: Anti Qa-1 Monoclonal Antibodies Technical Details: Dr. Soloski's laboratory has been interested for a number of years in the function of non-polymorphic class Ib molecules. For the last few years we have focused on the murine non-polymorphic molecule Qa-1b encoded by the gene H2-T23. The "b" superscript represents the particular allele of...

Published: 3/13/2025 | Inventor(s): Mark Soloski, Helena Ong

Keywords(s): Antibodies, Basic Research Biomarker, Cell Lines, Discovery/Research Tools, In Vitro Research Tool, Monoclonal Antibodies, Mouse Cell Lines, Research Reagent, Therapeutic Matter, Therapeutic Substance Synthesis Method, Therapeutics

Category(s): Technology Classifications > Research Tools, Technology Classifications > Research Tools > Antibodies