Search Results - technology+classifications+%3e+research+tools+%3e+research+stem+cells

6 Results

Sort By:

Multi-Compartment Fallopian Tube Organoid Model

Unmet Need: Existing organoid models of the fallopian tube are architecturally simplified compared to the intricate epithelial-lumen interface in scale and structure, and there remains a need in the art for multi-compartment fallopian tube organoids that architecturally simulate the intricate architecture of the epithelial-lumen interface in structural...

Published: 3/14/2025 | Inventor(s): Meng Horng Lee, Gabriella Russo, Denis Wirtz, Ashleigh Crawford, Wenxuan Du

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Medical Devices, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools > Research Stem Cells, Technology Classifications > Research Tools > Microfluidics, Clinical and Disease Specializations > Oncology

Clinical-Grade Therapeutic Progenitors Generated from Universal Donor Tankyrase/PARP-Inhibited Pluripotent Stem Cell Banks

Unmet Need / Invention Novelty: Regenerative cell therapies with conventional, lineage-primed human induced pluripotent stem cells (hiPSC) are limited by variable differentiation efficiency and poor in vivo functionality. There is an unmet need to establish novel methods for efficiently generating functional and transplantable therapeutic progenitors. Technical...

Published: 3/14/2025 | Inventor(s): Elias Zambidis, Ludovic Zimmerlin

Keywords(s):

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Stem Cells, Technology Classifications > Research Tools > Research Stem Cells

3D Shell MEAs for Electrically Active Organoids

Value Proposition· 3D shell MEAs is a novel platform for encapsulation, electrical stimulation, and recording of organoids· Electrophysiological measurements of electrically active 3D organoids. · Relevant to brain development, neurological disorders, drug screening; neuromorphic computing and brain-machine interfaces; and organoid...

Published: 3/14/2025 | Inventor(s): David Gracias, Lena Smirnova, Qi Huang

Keywords(s):

Category(s): Clinical and Disease Specializations > Autoimmunity, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Neurology > Motor Neuron Diseases, Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Clinical and Disease Specializations > Neurology > Neurodegeneration, Clinical and Disease Specializations > Neurology > Neuropathy, Technology Classifications, Technology Classifications > Research Tools > Stem Cells, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Research Stem Cells

Human IPSC-Based Drug Testing Platform for Duchenne Muscular Dystrophy

Unmet NeedThe development of new drugs is a capital and time intensive process. For this reason, the development of orphan drugs for those diseases that affect a small subset of the population. One of such diseases, Duchenne’s muscular dystrophy (DMD) affects 1 in 5000 boys worldwide and has no known cure. Current drug screen platforms include animal...

Published: 3/14/2025 | Inventor(s): Gabsang Lee, Kathryn Wagner, Congshan (Sunny) Sun

Keywords(s): Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Muscular Disorders, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Research Tools > Research Stem Cells

Generation of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells

Unmet NeedFuchs’ dystrophy, a progressive, hereditary disease of the cornea, is the leading cause of corneal transplants both in the US and worldwide. The disease results in the dysregulation and destruction of corneal endothelial cells which are responsible for keeping the eye properly hydrated. As the disease progresses, patients will experience blurred...

Published: 3/14/2025 | Inventor(s): Sheikh Amer Riazuddin, John Gottsch, Shahid Khan, Muhammad Ali

Keywords(s): Biologics, Cell Therapy, Corneal Dystrophy, Disease Indication, Eye Disorders, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Whole cell

Category(s): Clinical and Disease Specializations > Ophthalmology > Corneal Dystrophy, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Research Tools > Research Stem Cells

Partitioning of Human Mesenchymal Stem Cells based on CD107a Expression

JHU Ref #: C15392Value PropositionImproved Stem Cell Isolation: Enables efficient and scalable separation of stem cells predisposed to fat or bone tissue regeneration.Clinically Feasible: Uses magnetic-activated cell sorting (MACS), a cost-effective and translational alternative to fluorescence-activated cell sorting (FACS).Enhanced Therapy Potential: Optimized...

Published: 3/14/2025 | Inventor(s): Aaron James

Keywords(s): Cell Lines, Discovery/Research Tools, Human Cell Lines, In Vitro Research Tool

Category(s): Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools > Research Stem Cells