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System and Method for Antimicrobial Drug Susceptibility Screening at the Bedside

Value Proposition· Faster, same‑day guidance for prescribing antibiotics: Rapid bedside screening platform that captures cultures and tests bacteria from clinical specimens (e.g., urine) to inform immediate antibiotics prescribing in doctors’ offices, urgent care, and outpatient clinics.· Useful for low‑volume infections: Because the system...

Published: 3/13/2026 | Inventor(s): Andrew Feldman, Hannah Gray, Jeffrey Lin, Charles Young

Keywords(s): Bacterial Infections, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Point of Care

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Precision Medicine Tools, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Applied Physics Laboratory > Applied Physics Laboratory

RelA Inhibitor as a Anti-microbial Therapy

Value Proposition:· Unique mechanism of action that targets antibiotic-resistant infections· Ability to target multiple stress resistance mechanisms in bacteria· Broad range of application Technology Description· Researchers at Johns Hopkins have developed an antibacterial small molecule inhibitor that can be used to treat...

Published: 3/13/2026 | Inventor(s): Nathan Archer, Garth Ehrlich, Donald Hall

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases

Breathable Nanomedicine: Inhalable Angiotensin Blockers for Treating COVID-19 and Respiratory Infections

Value Proposition· Provides targeted pulmonary delivery with superior lung pharmacokinetics· Offers mutation-resistant therapeutic action, unlike current vaccines· Reduces risk of progression to severe lung disease in newly diagnosed patients· Applicable to a wide range of respiratory infections and ARDS-related conditions· Enhances...

Published: 3/13/2026 | Inventor(s): Jung Soo Suk, Daiqin Chen, Joe DiCostanzo, Axel Lehrer, Oreola Donini

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Clinical and Disease Specializations > Infectious Diseases > Respiratory Infections, Clinical and Disease Specializations > Respiratory Diseases, Clinical and Disease Specializations > Respiratory Diseases > Acute Respiratory Distress Syndrome, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Targets

Short Viral RNAs (svRNAs) with Theragnostic Potential in Infection with SARS-CoV-2 and Related Viruses

Value PropositionNovel Biomarkers for Diagnosis & PrognosisInsights into viral immune evasion mechanism Identify key host pathways targeted by svRNAs Novel Therapeutic TargetsIdentified pathways enable the development of immune-modulating therapies. Unmet NeedStudies have show than SARS-CoV-2 employs various mechanisms to evade the host’s innate...

Published: 3/13/2026 | Inventor(s): Kenneth Witwer, Tom Driedonks, Andrey Turchinovich

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Therapeutic Modalities, Technology Classifications > Research Tools > Nucleic Acids, Clinical and Disease Specializations > Infectious Diseases

Innovative Suit Designs and Doffing Methodologies for Personal Protective Equipment to prevent the spread of Ebola to Health Care Workers

Value Proposition· Increased safety: features back seam entry and exit with integrated doffing and disposal methods to reduce risk of contamination.· Easy to use: Simplified doffing decreases the complexity and time required to doff PPE.· Customizable and comfortable: Design includes sizing adjustments, sweat-wicking features, and...

Published: 3/12/2026 | Inventor(s): Youseph Yazdi, Melody Tan, Matthew Petney, William Patterson, Siavash Parkhideh, Jill Andrews, Patience Osei, Chandrakant Ruparelia, Harshadkumar Sanghvi, Timothy Harrigan, Nahyun Cho, Qian Liu, Sami Messai, Brian Ma, Meagan Hawes, Reeve Heinis, Jason Johnson, Erin Reisfeld, Arjun Vachhani, Timothy Campbell, Neil Rens, Madeleine Clegg, Elizabeth Stokley, Jessica Jeang, Christopher Chiang, Willibrord Shasha, Bailey Topper, Kimberly Ashman, Michael Parlato, Brandon Craft, Paul Fearis, Soumyadipta Acharya

Keywords(s): Disease Indication, Ebola, Industrial Manufacturing, Infectious Diseases, Manufactured Devices, Personal Protective Equipment (PPE), Safety Suits, Viral Infections

Category(s): Clinical and Disease Specializations, Technology Classifications > Industrial Tech > Industrial Manufacturing, Technology Classifications > Industrial Tech, Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Infectious Diseases > Ebola, Clinical and Disease Specializations > Infectious Diseases > Viral Infections, Technology Classifications > Engineering Tech > Industrial Manufacturing

A mRNA Lipid Nanoparticle Incorporated Nanofiber-hydrogel Composite to Generate a Local Immunostimulatory Niche for Immunotherapy

Value Proposition:· Creates a programmable immunostimulatory niche.· Allows for tailor-made immune responses to vaccines and antigens.· Flexible drug delivery platform enables mRNA therapeutics for infectious diseases and cancers.· Applicable to existing mRNA vaccines for improved efficacy. · Can be utilized for novel...

Published: 3/13/2026 | Inventor(s): Hai-Quan Mao, Yining Zhu, Jingyao Ma, Zhicheng Yao, Christine Wei

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Research Tools, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Vaccines, Technology Classifications > Research Tools > Microfluidics

Self-Assembling Antiviral Prodrugs for Long-Acting Treatment of Chronic HIV Infections

Unmet Need / Invention Novelty: The need for long-acting HIV drugs arises from challenges such as pill burden, side effects, and stigma, which contribute to inconsistent use and reduced effectiveness. A long-acting antiretroviral formulation could enhance treatment adherence, reduce disease transmission, and better support populations facing barriers...

Published: 3/13/2026 | Inventor(s): Honggang Cui, Charles Flexner, Maya Monroe, Han Wang

Keywords(s):

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Peptides, Clinical and Disease Specializations > Infectious Diseases > HIV, Clinical and Disease Specializations > Infectious Diseases > HIV/AIDS, Clinical and Disease Specializations > Infectious Diseases > Hepatitis B Virus, Clinical and Disease Specializations > Infectious Diseases > Viral Infections

Novel Oxazolidinone Antibacterials and the Synthetic Routes to Them

Marketing Summary Draft Novel Oxazolidinone Antibacterials and the Synthetic Routes to ThemJHU Ref #: C18144Value Proposition· Higher efficacy and lower toxicity oxazolidinone compounds· Positive activity demonstrated against M. abscessus· MIC values are the same or better than the current antibiotics in the market Unmet Need The...

Published: 3/13/2026 | Inventor(s): Gyanu Lamichhane, J. Ippoliti, Cole Friederichs, Connor Winkelhake, Ben Thompson, Kelsey Latterell

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases

Novel Oxazolidinones for Treatment of Bacterial Infections

Marketing Summary DraftNovel Oxazolidinones for Treatment of Bacterial InfectionsJHU Ref #: C14633Value Proposition· Belong to the same chemical family as Zyvox, marketed by Pfizer, but shows better efficacy· Positive activity demonstrated against M. tuberculosis· MIC values the same or better than the current antibiotics in the...

Published: 3/13/2026 | Inventor(s): Gyanu Lamichhane, J. Ippoliti

Keywords(s): Bacterial Infections, Disease Indication, Infectious Diseases, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections

Polymers and Nanoparticles for Intramuscular Nucleic Acid Delivery

Value Proposition:· Platform technology for prophylactic and therapeutic vaccination with large RNA payloads.· Can deliver several types of nucleic acid payloads including self-amplifying mRNA, plasmid, linear DNA, siRNA, miRNA, mRNA.· Adaptable as a therapeutic delivery strategy for genetic, musculoskeletal, and neurological disorders.Unmet Need:Vaccinology...

Published: 3/13/2026 | Inventor(s): Jordan Green, David Wilson, Stephany Tzeng, Yuan Rui, Sarah Neshat, Kathryn Luly

Keywords(s):

Category(s): Clinical and Disease Specializations > Immunology, Clinical and Disease Specializations > Infectious Diseases

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