Search Results - technology+classifications+%3e+research+tools+%3e+imaging

14 Results

Sort By:

18F-Labeled PET Radiotracers for Imaging Neuroinflammation in the Brain

Value Proposition:· Quantification and PET imaging of microglial cells in the brain· Diagnostic for neuroinflammatory disorders – Alzheimer’s and MS· Favorable compound half-life enables shipping· Potential for non-CNS applications Technology DescriptionResearchers at Johns Hopkins have developed a series of Positron Emission Tomography...

Published: 6/28/2024 | Inventor(s): Martin Pomper, Deepankar Das, Andrew Horti, Wojciech Lesniak

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology, Technology Classifications, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging

High Throughput Single Cell Resolution Analysis Software

Unmet NeedBiological research relies on accurate and precise image analysis, from tracking cells over time, assessing changes to organelles under experimental conditions, to quantifying localization of immunofluorescence. As imaging technology advances and biological questions become more detailed, a massive amount of high-resolution data is acquired...

Published: 6/28/2024 | Inventor(s): Gordon Sun

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Research Tools > Imaging

Myelin Protein Zero (MPZ)-targeting Compounds and Uses Thereof

Unmet NeedPeripheral nerve injuries require optimally timed intervention to maximize functional recovery and minimize permanent nerve death and negative impacts to quality of life. Current treatment plans rely primarily on monitoring for spontaneous healing or an indication that there must be surgical intervention, an approach that hinges on accurate...

Published: 6/28/2024 | Inventor(s): Martin Pomper, Catherine Foss, Sami Tuffaha, William Padovano, Bei Cheng

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Neuropathy, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging

Workflow for Targeted Analysis of Image Mass Cytometry

Technology Description· Researchers at Johns Hopkins have developed a streamlined workflow for performing targeted imaging in image mass cytometry (IMC) with improved region of interest (ROI) selection. · This approach for ROI identification uses adjacent stained sections (e.g., H&E, PAS) with more prominent tissue features as a guide.· ROI...

Published: 6/28/2024 | Inventor(s): Pei-Hsun Wu, Denis Wirtz, Won Jin Ho

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Imaging

Acoustic Frequency-Based Spectral Unmixing to Determine Tissue Constituents

Unmet Need:The demarcation between target tissue to be removed, and healthy tissue to leave intact, is critical to the success of any surgical procedure. These operations are often performed using high-resolution imaging, including MRI or CT scans. Such methods provide a priori information to clinicians; however, these methods yield limited information...

Published: 6/28/2024 | Inventor(s): Muyinatu Bell, Eduardo Gonzalez

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Surgery, Technology Classifications > Research Tools > Imaging, Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Surgery

Simultaneous Material Decomposition for Motion-free, High-performance Digital Subtraction Angiography

Unmet Need· Digital subtraction angiography (DSA) is an imaging technique that utilizes a contrast agent and subtraction of radiopaque structures (like bone) to visualize blood vessels for the assessment of cardiovascular disease (Stanford). However, due to involuntary motion of soft tissue, this subtractive measure is often misregistered, leading...

Published: 6/28/2024 | Inventor(s): Jianan Gang, Joseph Stayman

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Research Tools > Imaging

Spectral DSA

Unmet NeedCT angiography with digital subtraction (DSA) is the standard diagnostic imaging method for cardiovascular abnormalities (1). This technique captures images both before and after injection of radiopaque contrast; images are then subtracted from one another, leaving only contrast enhanced vasculature in the final image. While DSA is the gold...

Published: 6/28/2024 | Inventor(s): Joseph Stayman, Jianan Gang

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Research Tools > Imaging, Clinical and Disease Specializations > Cardiovascular > Aneurysm, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Clinical and Disease Specializations > Neurology > Cerebral Aneurysm, Clinical and Disease Specializations > Neurology > Cerebral Ischemia, Clinical and Disease Specializations > Neurology > Hemorrhage

Methods for Payload and Size Characterization of Nucleic Acid Nanoparticles

Polymeric and lipid nanoparticles (NPs) are an effective and safe method for therapeutic delivery. At each of the various steps in nanoparticle development and manufacturing (i.e., research and design, quality assurance), assessing the features of these vehicles is essential. Some features (i.e., packaging characteristics, cargo location, structure...

Published: 6/28/2024 | Inventor(s): Tza-Huei Wang, Hai-Quan Mao, Sixuan Li, Yizong Hu, Andrew Li

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Research Tools > Imaging, Technology Classifications > Research Tools > Nucleic Acids

Bias-Tolerant Imaging

Unmet NeedComputed tomography (CT) is one of the primary imaging modalities used to image focal liver lesions and assess the efficacy of oncological therapy. Typically, patients are scanned using iodine contrast-enhanced CT, where the change in lesion size over time is an indicator of therapeutic efficacy. However, exclusively relying on lesion size...

Published: 6/28/2024 | Inventor(s): Joseph Stayman, Jianan Gang

Keywords(s):

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Research Tools > Imaging

Snapshot Hyperspectral Imager for Emission and Reactions (SHEAR)

Unmet Need:Measuring the output of combustion reactions is essential for the understanding of reaction mechanisms and the burn characteristics of a reaction. This is especially valuable when measuring the combustion of metal fuels such as Al, B, Mg, Zr, Ti. Currently available systems including spectroscopy and pyrometry are limited in their spatial...

Published: 6/28/2024 | Inventor(s): Mark Foster, Milad Alemohammad, Elliot Wainwright, Timothy Weihs, Jasper Stroud

Keywords(s):

Category(s): Technology Classifications > Research Tools > Imaging, Technology Classifications > Engineering Tech > Energy, Infrastructure & Environment

1 2