Search Results - other+virus

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Single Vector Genome Editing with CRISPR/Cas and BacMam

Unmet NeedTargeted, site-specific genome editing is an important scientific tool with broad applications in basic science, the pharmaceutical industry, and translational medicine. It enables the addition of florescent or other types of gene tags for purification, visualization, or tracking. Genome editing can also introduce novel functions for endogenous...

Published: 6/27/2025 | Inventor(s): Chulan Kwon, Renjun Zhu, Amir Saberi

Keywords(s): Basic Research Biomarker, Cloning Reagents, Discovery/Research Tools, Other Virus, Plasmid, Research Reagent, Translational Research Biomarker, Viruses

Category(s): Technology Classifications > Research Tools > Vectors & Plasmids, Technology Classifications > Research Tools > Viruses

TC-1 (Po)

C03436: TC-1 (Po) Technical Details:This cell line "was developed to circumvent the confounding issue of negatively selecting nonessential tumor markers in cancer vaccine experiments. Primary lung epithelial cells from C57BL/6 mice were immortalized with HPV-16 E6 and E7 and then transformed with the activated ras oncogene. This transformation...

Published: 6/26/2025 | Inventor(s): T.c. Wu

Keywords(s): Basic Research Biomarker, Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Mouse Cell Lines, Other Virus, Research Reagent, Viruses

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Viruses

Human Papillomavirus Virus-like-participle Protein

TITLEHuman Papillomavirus Virus-like-participle ProteinCASE NUMBERC04137ABSTRACTVirus-like particles (VLPs) are extraordinary molecules that resemble and mimic the structure of authentic viruses without being infectious. Since they do not contain any viral genetic material, they are able to elicit a strong immune response, without doing any actual...

Published: 6/26/2025 | Inventor(s): Raphael Viscidi

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, Disease Indication, Human Papillomavirus, Human Papillomavirus (HPV), Infectious Diseases, Other Virus, Research Reagent, Viral Infections, Viruses

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Human Papillomavirus, Clinical and Disease Specializations > Infectious Diseases > Viral Infections, Technology Classifications > Research Tools > Viruses, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools

Polyomavirus Like-particles for Diagnostics and Antibody Development

Novelty: This tangible material is polyomavirus virus like-particles that can be used to measure human antibodies to polyomaviruses in diagnostic assays and to introduce polyomavirus capsid specific antibodies by immunization.Value Proposition: Merkel cell polyomavirus (MCPyV) is a recently discovered polyomavirus in Merkel Cell Carcinoma, a rare and...

Published: 6/26/2025 | Inventor(s): Raphael Viscidi

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, Disease Indication, Infectious Diseases, Other Virus, Research Reagent, Viral Infections, Viruses

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Viral Infections, Technology Classifications > Research Tools > Viruses, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools

Luciferase-tagged Cytomegalovirus (CMV) for High-throughput Drug Screening

Novelty: Luciferase-tagged CMV strains for rapid sensitive anti-CMV drug screening.Value Proposition: To date, the identification of anti-viral agents for cytomegalovirus (CMV), a major threat in immunocompromised people and congenitally-infected children, relies on evaluation of viral replication via plaque assays and real-time PCR. However, these...

Published: 6/26/2025 | Inventor(s): Ravit Boger, Gordon Sandford, Gary Hayward, William Burns

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vitro Research Tool, Labels/Markers, Other Virus, Research Reagent, Target-based Screening Tool, Viruses

Category(s): Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Viruses, Technology Classifications > Diagnostics, Technology Classifications > Research Tools > Assays

SIV Clonal Isolates: SIV/17E-Fr, SIV/17E-C1, SIV/3-11RG, and SIV/3-7

C04943: SIV Clonal Isolates: SIV/17E-Fr, SIV/17E-C1, SIV/3-11RG, and SIV/3-7 Technical Details: JHU researchers have constructed infectious simian immunodeficiency virus (SIV) molecular clones that differ in their Env and Nef proteins. These clones display differences in neurovirulence and cellular tropism.Looking for Partners: SIV clones for...

Published: 6/26/2025 | Inventor(s): Janice Clements

Keywords(s): Cloning Reagents, Discovery/Research Tools, Disease Indication, Infectious Diseases, Nucleotide, Other Virus, Plasmid, Research Reagent, Translational Research Biomarker, Viruses

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools > Nucleic Acids, Technology Classifications > Research Tools > Viruses, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Vectors & Plasmids

Novel Genes of Kaposi's Sarcoma Associated Herpesvirus (Human Herpesvirus Eight)

C03120: Novel Genes of Kaposi's Sarcoma Associated Herpesvirus (Human Herpesvirus Eight) Technical Details: Karposi sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV-8) is a virus commonly occurring in AIDS patients and closely associated with Karposi’s sarcoma (KS), body cavity based lymphomas (BCBL), multiple myeloma, and multicentric...

Published: 6/26/2025 | Inventor(s): Marvin Reitz, J. Hardwick, John Nicholas, Gary Hayward

Keywords(s): Cancers, Discovery/Research Tools, Disease Indication, Kaposi's Sarcoma, Kaposi's Sarcoma-Associated Herpesvirus, Other Virus, Research Reagent, Translational Research Biomarker, Viruses

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Kaposi's Sarcoma-Associated Herpesvirus, Clinical and Disease Specializations > Oncology > Kaposi's Sarcoma, Technology Classifications > Research Tools > Viruses, Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools