Search Results - polycystic+kidney+disease

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Polyclonal Chicken and Rabbit Antibodies, Termed Anti-CC, Generated Using Denatured C-terminal 199 Amino Acid Fragment of Mouse Polycystin-1 Protein as Immunogen

TITLE Polyclonal chicken and rabbit antibodies, termed anti-CC, of mouse polycystin-1 protein as immunogenC13399ABSTRACTPolycystin-1 (PC1) has an essential function in renal tubular morphogenesis and disruption of its function causes cystogenesis in human autosomal dominant polycystic kidney disease. Endogenous...

Published: 3/13/2025 | Inventor(s): Feng Qian

Keywords(s): Antibodies, Basic Research Biomarker, Biomarker, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics, In Vitro Research Tool, In Vivo Research Tool, Kidney Disorders, Polyclonal Antibodies, Polycystic Kidney Disease, Rabbit Model, Rabbit Model Xenograft, Research Reagent, Target-based Screening Tool

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools, Clinical and Disease Specializations > Nephrology > Polycystic Kidney Disease

Pkd1(superscript ko) Mouse Line (Pkd1[superscript tm1Ggg]; it is also known as Pkd1[superscript beta-gal-null])

C10754: Mouse Model For Polycystic Kidney Disease Gene KnockoutNovelty: This technology is a mutant mice containing beta-galactosidase instead of Pkd1 gene to study the pathogenesis of autosomal dominant polycystic kidney disease.Value Proposition: Autosomal dominant polycystic kidney disease is characterized by cyst formation in the kidney and other...

Published: 3/13/2025 | Inventor(s): Klaus Piontek, Gregory Germino

Keywords(s): Basic Research Biomarker, Biomarker, Cell Lines, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics, In Vitro Research Tool, In Vivo Research Tool, Kidney Disorders, Knock Out Mouse Model, Mouse Cell Lines, Mouse Model, Polycystic Kidney Disease

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Clinical and Disease Specializations > Nephrology > Polycystic Kidney Disease, Technology Classifications > Diagnostics > Biomarkers