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Search Results - proteomics%2fimmunoassays
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Assay to Screen for ZnT8 Modulators to treat T2D and Other Diseases
Unmet Need: Prevalence of Type 2 Diabetes (T2D) continues to rapidly increase worldwide, contributing significant economic and global health burdens. There is an urgent need for the development of novel therapeutic strategies to treat T2D.Technical Details: Johns Hopkins researchers have identified a novel target to treat T2D and report here the development...
Published: 6/12/2026
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Inventor(s):
Dax Fu
,
Chengfeng Merriman
Keywords(s):
Analytical Method
,
Diabetes
,
Discovery/Research Tools
,
Disease Indication
,
In Vitro Research Tool
,
Metabolic Disorders
,
Proteomics/Immunoassays
,
Research Reagent
,
Target-based Screening Tool
,
Type II Diabetes
Category(s):
Clinical and Disease Specializations > Diabetes > Type 2 Diabetes
,
Technology Classifications > Research Tools > Assays
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Technology Classifications > Therapeutic Modalities > Targets
Polyclonal Antibodies For CD25-Expressed Cancers
Value PropositionBinds a potential novel target for pharmacological interventions, as monoclonal antibodies against CD25 are a significant treatment for C25 expressed cancers.Reports phosphorylation of S113 and S117 residues in Sam68, which is critical for the NF-kB-mediated selective transcription of the CD25 gene.Unmet NeedAnnually, there are approximately...
Published: 6/12/2026
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Inventor(s):
Fengyi Wan
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Discovery/Research Tools
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antibodies
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Assays
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Technology Classifications > Research Tools
Anti-TARP Gamma 8 pAb
Invention novelty: This technology is an anti-TARP [transmembrane alpha-amino-3-hydroxyl-5-isoxazolepropionate (AMPA) receptor protein] gamma 8 polyclonal antibody.Value Proposition: In many neurological diseases, AMPA receptor function and structure are altered. This arrangement makes AMPA receptors potential therapeutic targets for clinical intervention. This...
Published: 6/12/2026
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Inventor(s):
Richard Huganir
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
CNS and Neurological Disorders
,
Discovery/Research Tools
,
Disease Indication
,
Polyclonal Antibodies
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antibodies
,
Research Reagent
,
Translational Research Biomarker
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Assays
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Technology Classifications > Research Tools
,
Clinical and Disease Specializations > Neurology
Mouse Anti-LAG3 Monoclonal Antibody (4-10-C9)
C11691: Mouse LAG-3 Monoclonal AntibodyNovelty: A mouse monoclonal antibody (mAb) against LAG-3 (Lymphocyte Activation Gene 3).Value Proposition: LAG-3 is expressed on the cell surface of activated T-cells and is known to be an important global regulatory molecule that controls many aspects of T-cell proliferation and homeostasis. This invention is...
Published: 6/12/2026
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Inventor(s):
Dario Vignali
,
Charles Drake
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Discovery/Research Tools
,
Monoclonal Antibodies
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antibodies
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Assays
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Technology Classifications > Research Tools
mAb to mouse MICAL-1 and mouse MICAL-3
C11198: mAb to mouse MICAL-1 and mouse MICAL-3Value Proposition: JHU inventors have developed mouse monoclonal antibodies directed against mouse MICAL-1 and MICAL-3 proteins. These antibodies may be used in experiments involving these proteins and could also be optimized for other procedures.
Published: 6/12/2026
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Inventor(s):
Qiang Wang
,
Rajnish Bharadwaj
,
Alex Kolodkin
Keywords(s):
Antibodies
,
Basic Research Biomarker
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CNS and Neurological Disorders
,
Discovery/Research Tools
,
Disease Indication
,
Monoclonal Antibodies
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antibodies
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Assays
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Technology Classifications > Research Tools
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Clinical and Disease Specializations > Neurology
Polyclonal Antisera Specific for Neuropilin-1 and Polyclonal Antisera Specific for Neuropilin-2
C10703: Polyclonal Antibodies for Neuropilin-1 (Npn-1) and Polyclonal Antibodies for Neuropilin-2 (Npn-2)Value Proposition: These are rabbit polyclonal antibodies directed against the rodent proteins neuropilin-1 and neuropilin-2. The neuropilins are semaphorin receptors.Technical Details: The semaphorin family contains a large number of phylogenetically...
Published: 6/12/2026
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Inventor(s):
David Ginty
,
Alex Kolodkin
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Discovery/Research Tools
,
Polyclonal Antibodies
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antibodies
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Assays
,
Technology Classifications > Research Tools
Rabbit Serum 5690
C10529: Rabbit Serum 5690: Antibodies Against Rat Lmo7Value Proposition: • Polyclonal antibodies against rat Lmo7Technical Details: Nuclear lamina is a dense fibrillar network inside the nucleus of eukaryotic cells composed of intermediate filaments (lamins) and membrane associated proteins called lamin-associated membrane proteins. The nuclear lamina...
Published: 6/12/2026
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Inventor(s):
Katherine Wilson
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Discovery/Research Tools
,
Disease Indication
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Genetic Disorders
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Muscular Disorders
,
Peptides
,
Polyclonal Antibodies
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antiserum
,
Recombinant Proteins
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Assays
,
Technology Classifications > Research Tools
,
Technology Classifications > Research Tools > Proteins, Ligands & Receptors
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Clinical and Disease Specializations > Genetic Diseases
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Clinical and Disease Specializations > Rare Diseases
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Clinical and Disease Specializations > Musculoskeletal
Rabbit Serum 5688
C10528: Rabbit Serum 5688: Antibodies Against Rat Lmo7Value Proposition: •Polyclonal antibodies against rat Lmo7Technical Details: Nuclear lamina is a dense fibrillar network inside the nucleus of eukaryotic cells composed of intermediate filaments (lamins) and membrane associated proteins called lamin-associated membrane proteins. The nuclear lamina...
Published: 6/12/2026
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Inventor(s):
Katherine Wilson
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Discovery/Research Tools
,
Polyclonal Antibodies
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antiserum
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Assays
,
Technology Classifications > Research Tools
Rat Serum 4279
C10526: Rat Serum 4279: Antibodies Against Human MAN1Value Proposition: • Polyclonal antibodies against human MAN1Technical Details: Nuclear lamina is a dense fibrillar network inside the nucleus of eukaryotic cells composed of intermediate filaments (lamins) and membrane associated proteins called lamin-associated membrane proteins. The nuclear lamina...
Published: 6/12/2026
|
Inventor(s):
Katherine Wilson
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Discovery/Research Tools
,
Polyclonal Antibodies
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antiserum
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Assays
,
Technology Classifications > Research Tools
Rabbit Serum 4278
C10525: Rabbit Serum 4278: Antibodies Against Human MAN1 Technical Details: Nuclear lamina is a dense fibrillar network inside the nucleus of eukaryotic cells composed of intermediate filaments (lamins) and membrane associated proteins called lamin-associated membrane proteins. The nuclear lamina provides mechanical support, regulates important cellular...
Published: 6/12/2026
|
Inventor(s):
Katherine Wilson
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Discovery/Research Tools
,
Peptides
,
Polyclonal Antibodies
,
Proteomics/Immunoassays
,
Proteomics/Immunoassays
Antiserum
,
Recombinant Proteins
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Assays
,
Technology Classifications > Research Tools
,
Technology Classifications > Research Tools > Proteins, Ligands & Receptors
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