Search Results - clinical+and+disease+specializations+%3e+wound+healing

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Value Proposition· Flexibility to be combined with various types of topical medications or delivery mechanisms· Easily manufactured key ingredients Unmet Need· Chronic wounds persist for long periods of time without adequate healing response. They may take various forms, such as vascular ulcers, diabetic foot ulcers, or sacral pressure...

Published: 3/13/2026 | Inventor(s): Luis Garza, Gaofeng Wang

Keywords(s):

Category(s): Clinical and Disease Specializations > Dermatology > Pressure Ulcer, Clinical and Disease Specializations > Dermatology, Clinical and Disease Specializations > Diabetes, Clinical and Disease Specializations > Wound Healing

Use of Non-labeled Sugars in MRI

Value Proposition: ADVANTAGES: • Provides an alternative approach to measure MR contrast sensitive to both metabolic and vascular properties (perfusion and permeability) of tissue. • Uses a natural biodegradable compound that is already available in the clinic, without the need for paramagnetic, magnetic, or radioactive isotope labeling....

Published: 3/12/2026 | Inventor(s): Guanshu Liu, Dmitri Artemov, Yoshinori Kato, Kannie Chan, Michael Mcmahon, Peter van Zijl

Keywords(s): Disease Indication, Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI), Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

The Role of IL17 in Age-related Immune-stromal Network Inhibiting Response to Regenerative Immunotherapy

Combination immunotherapy to enhance tissue regeneration in the elderly JHU Ref #: [C17006] Value Proposition· Regenerative medicine strategies aim to restore or replace damaged tissues and organs, with patients suffering from chronic diseases, injuries, and degenerative conditions as the end-users of regenerative medicine therapies.· Current...

Published: 3/13/2026 | Inventor(s): Jennifer Elisseeff, Jin Han, Christopher Cherry, Drew Pardoll

Keywords(s):

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Fibrosis, Clinical and Disease Specializations > Inflammation, Clinical and Disease Specializations > Traumatic Injury, Clinical and Disease Specializations > Wound Healing

Thermosensitive Hydrogel-Nanoparticle System to Reverse Cellular Senescence and Enhance Collagen Production

Value Proposition:Provides a slow, sustained release of a combination therapy to reverse cellular senescence and enhance collagen production in proliferating and senescent primary dermal fibroblasts.Utilizes a thermosensitive and biodegradable hydrogel for sustained release of nanoparticles and drugs.Requires fewer applications compared to traditional...

Published: 3/13/2026 | Inventor(s): Efrosini Kokkoli, Peter Abadir, Jeremy Walston, Paul Kuhn

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Cell Therapies, Clinical and Disease Specializations > Diabetes, Clinical and Disease Specializations > Wound Healing

Delayed Lagging Strand Synthesis Promotes Male Fertility during Aging

Inhibition-based Method for Stem Cells Induction from Non-Stem Cells Value Proposition:· Induces stem cells from non-stem cells through modification of gene expression or function. · Relies on influencing a single DNA replication component rather than multiple molecular factors.· Successfully rescues both male and female fertility in...

Published: 3/13/2026 | Inventor(s): Xin Chen, Brendon Davis, Rajesh Ranjan

Keywords(s):

Category(s): Clinical and Disease Specializations > Reproductive Health > Fertility, Clinical and Disease Specializations > Wound Healing

Dynamic Hydrogels

Unmet NeedOrgan/tissue regeneration remains a major area of research with few viable clinical products. A major barrier is the development of biologically accurate tissue constructs, with vascularization being a primary component. Classic static hydrogels have non-reversible crosslinks such that network is elastic at the macro-scale but limited in response...

Published: 3/13/2026 | Inventor(s): Sharon Gerecht, Rahel Schnellmann, Zhao Wei, Eugenia Volkova

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Therapeutic Modalities > Tissue Substrates, Clinical and Disease Specializations > Wound Healing, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases

Nanoparticle Compositions for Sustained Delivery of Pro-regenerative Growth Factors for Nerve Repair, Preparation Processes of the Same, and Treatment Methods Using the Same

Unmet NeedGlobal incidence rates for peripheral nerve injury (PNI) are not well aggregated. However, US data collected shows that 20 million Americans suffer from peripheral nerve injury caused by trauma and medical disorders. [16] When a tension-free early repair is possible, microsurgical direct nerve repair with epineural sutures remains the gold...

Published: 3/13/2026 | Inventor(s): Hai-Quan Mao, Sami Tuffaha, Chenhu Qiu, Sashank Reddy, Yicheng Zhang, Thomas Harris, Philip Hanwright, Karim Sarhane, Nicholas von Guionneau, Erica Lee

Keywords(s):

Category(s): Clinical and Disease Specializations > Wound Healing, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

Multiphase Transitioning Peptride Hydrogel for Use in Vascular Anastamosis

Unmet NeedThe formation of vascular anastomosis, the joining of two blood vessels, is a fairly common procedure utilized by many surgeons. All vascular bypass operations and solid organ transplants require anastomoses. However, as the vessels being anastomosed become smaller or less firm, surgeons have exponentially increasing rates of failure. In...

Published: 3/12/2026 | Inventor(s): Daniel Smith, Johanna Grahammer, Joel Schneider, Gerald Brandacher, Gabriel Brat

Keywords(s): Disease Indication, Implanted Device, Implants, Therapeutic Devices, Therapeutics, Tissue Engineering/Regenerative Devices, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices

Non-immunosuppressive FK506 analogs and use thereof

Unmet NeedChronic, nonhealing wounds are estimated to affect approximately 2% of the general population, and the cost of caring for these wounds exceeds $50 billion per year. These costs are expected to rise due to the increasing prevalence of diabetes and other diseases that hinder wound healing. Chronic infections increase morbidity and mortality...

Published: 3/13/2026 | Inventor(s): Jun Liu, Zhaoli Sun, Brandon Peiffer, Yuefan Wang, Le Qi, Zufeng Guo, Hanjing Peng, Ali Ahmadi

Keywords(s): Antagonists/Inhibitors, Combination, Disease Indication, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutic Substance Synthesis Method, Therapeutics, Therapy Type, Transplants

Category(s): Clinical and Disease Specializations > Wound Healing, Technology Classifications > Therapeutic Modalities > Small Molecules

Cancer in Angiogenesis

Unmet NeedIn the United States alone, almost 8.5 million people suffer from peripheral artery disease (PAD). The market for PAD and Peripheral Vascular Disease (PVD) is expected to reach $378.53 million with a CAGR of 7.06% by 2024. Therapeutic angiogenesis are therapies aimed at growing new vessels into compromised tissue. Wound healing, PAD, and coronary...

Published: 3/13/2026 | Inventor(s): Andrew Schulick

Keywords(s): Biologics, Cardiovascular Diseases, Cell Model, Coronary Heart Disease, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Peripheral Artery Disease, Stem Cells, Therapeutic Matter, Therapeutic Substance, Therapeutic Substance Synthesis Method, Therapeutics, Whole cell, Wound Healing

Category(s): Technology Classifications > Therapeutic Modalities > Stem Cells, Clinical and Disease Specializations > Wound Healing, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Research Tools > Stem Cells

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