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Molecular Signature Diagnostic for Myocarditis

Value Proposition· High Diagnostic Sensitivity and Reproducibility: Detects a spatially diffuse molecular signature, defined by the upregulation of a distinct family of genes, enabling identification and stratification of myocarditis, of any sub-type· Molecular Reframing of Disease: Redefines myocarditis as a diffuse molecular state of...

Published: 3/13/2026 | Inventor(s): Luigi Adamo, Marc Halushka, Kevin Bermea, Charles Cohen

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System and Method for Antimicrobial Drug Susceptibility Screening at the Bedside

Value Proposition· Faster, same‑day guidance for prescribing antibiotics: Rapid bedside screening platform that captures cultures and tests bacteria from clinical specimens (e.g., urine) to inform immediate antibiotics prescribing in doctors’ offices, urgent care, and outpatient clinics.· Useful for low‑volume infections: Because the system...

Published: 3/13/2026 | Inventor(s): Andrew Feldman, Hannah Gray, Jeffrey Lin, Charles Young

Keywords(s): Bacterial Infections, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Point of Care

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Precision Medicine Tools, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Applied Physics Laboratory > Applied Physics Laboratory

A Preclinical Model of Radiotherapy-induced Brain Injury (RIBI) for the Evaluation of Potential RIBI Prophylactic and Therapeutic Agents

The rodent model described in the publication “Developing Magnetic Resonance Imaging Biomarkers of Neuroinflammation, Cognitive Impairment, and Survival Outcomes for Radiotherapy-Induced Brain Injury (RIBI) in a Preclinical Mouse Model” could play a critical role in enabling the better identification and characterization of noninvasive and clinically...

Published: 3/13/2026 | Inventor(s): Ethel Ngen

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Method for Making Ultrasonic Transducer Device

JHU Ref #: [C17108, C17833, and C17521]Value Proposition· Wearable, Patch-Based Technology: Designed to autonomously monitor and/or treat biological features, enabling rapid, non-invasive triage and care in emergency settings.· Three Sensing Modalities: A handheld device collects and displays the real-time physiological data of multiple...

Published: 3/13/2026 | Inventor(s): Amir Manbachi, Haley Abramson, Joshua Punnoose, Aliaksei Pustavoitau, Kelley Leadingham, Nicholas Nowicki, David Gerke, Jeff Corgan, George Coles

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GluR2 Y876F mouse line

Unmet Need:The ability of neurons to alter the strength of their synaptic inputs bidirectionally in response to different stimuli is known as synaptic plasticity. Synaptic plasticity allows the brain to encode and respond to different stimuli such as learning and memory. Synaptic strengthening and weakening are finely tuned by changes in α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic...

Published: 3/13/2026 | Inventor(s): Richard Huganir

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Category(s): Technology Classifications > Research Tools > Animal Models, Clinical and Disease Specializations > Neurology

Conditional expression of human SHH mouse

Unmet Need:Every year, approximately 6,000 children are born with Down syndrome worldwide (see CDC). Down syndrome is ubiquitously associated with cognitive delays, and sometimes accompanied by additional neurological defects (see NDSS). Unfortunately, little is known about how these cognitive deficits arise. Some studies suggest that sonic hedgehog...

Published: 3/13/2026 | Inventor(s): Roger Reeves, Donna Klinedinst, Fabian Fernandez, Feng Gao

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Category(s): Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices

Systems and Methods for Monitoring and Treatment of an Injury (HEPIUS)

JHU Ref #: [C15551, C17109, C17520, C17716]Value Proposition· Real-Time Physiological Monitoring: Provides continuous, high-resolution images of the spinal cord and microvasculature, enabling real-time assessment of spinal cord blood flow (SCBF) to determine points of intervention and mitigate secondary phase injury following spinal cord injury...

Published: 3/13/2026 | Inventor(s): Amir Manbachi, Nicholas Theodore

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Systems and Methods for Monitoring and Treatment of Injuries (HEPIUS Wearables)

Published: 3/13/2026 | Inventor(s): Amir Manbachi, Nicholas Theodore

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Analytical Design Approach for Radial-scanning Ultrasound and Photoacoustic Imaging Transducers

Value Proposition· Optimized Imaging Framework: Utilizes an analytical radial synthetic aperture focusing (rSAF) approach to provide the highest possible spatial resolution and image quality while minimizing grating lobe artifacts· Transformable Radius: Allows the transducer to contract during insertion for improved accessibility and expand...

Published: 3/13/2026 | Inventor(s): Jeeun Kang, Emad Boctor, Hyunwoo Song

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Organic Phase Wet-chemistry Synthesis of High-Entropy Alloy Nanoparticles

Value PropositionEfficient Synthesis: Produces high-entropy alloy nanoparticles under organic, solution-based conditions without the need for extreme conditions and specialized equipmentPrecision Control Platform: Offers tunable control over size, phase, shape, facets, and surface decoration, overcoming the limitations of traditional nonequilibrium-based...

Published: 3/13/2026 | Inventor(s): Chao Wang, Fei Xu

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