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Volumetric Interventional Tool Tracking and Patient Monitoring Method and Apparatus
Unmet NeedUltrasound-guided vascular access has also been shown to decrease cannulation time for emergent veno-arterial extracorporeal membrane oxygenation (VA-ECMO) cannulation in refractory cardiac arrest. Despite the increasingly widespread use of ultrasound for procedural guidance, reliable and accurate tracking of the device can be challenging...
Published: 3/14/2025   |   Inventor(s): Jeeun Kang, Emad Boctor, Laeben Lester, Keshuai Xu, Jintan Zhang
Keywords(s):  
Category(s): Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Computers, Electronics & Software
Methods for in situ Detection of DNA Sequence Variation
Value Proposition·        High-throughput·        Assess genetic variants with simultaneous spatial analysis·        Interrogate over 100 variants in a single assayUnmet Need·        Next generation sequencing has led to an ever-proliferating dearth of genetic information. More recent progress in nucleoside tissue analysis has birthed the field of spatial...
Published: 3/14/2025   |   Inventor(s): Reza Kalhor, Soichiro Asami
Keywords(s):  
Category(s): Technology Classifications, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Bioinformatics, Technology Classifications > Research Tools > Imaging, Technology Classifications > Research Tools > Nucleic Acids
Apparatus and Method for modular ultrasound and photoacoustic imaging and interactive guidance using a position-tracked modular imaging framework
Value Proposition·        Wearable ultrasound system that is adaptable to different patient physiologies and ages.·        Allows for longitudinal and non-invasive monitoring of internal organs of critical care patients.·        Applicable across a broad range of organ systems and disease indications.·        Simulation-aided interactive guidance simplifies...
Published: 3/14/2025   |   Inventor(s): Jeeun Kang, Emad Boctor, Ananya Tandri
Keywords(s):  
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Imaging
Non-contact Ultrasound Tomography Imaging System
Multifunctional 3D ultrasound imaging systemJHU Ref #: C17859Value Proposition:·        Generation of high resolution 3D images for detection and diagnosis of diseases.·        Overcomes previous required use of media (water) to image.·        Media-less imaging ability allows for integration of other imaging techniques (MRI, PET, CT). Unmet Need·        The...
Published: 3/14/2025   |   Inventor(s): Jeeun Kang, Emad Boctor, Hyunwoo Song, Yixuan Wu
Keywords(s):  
Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging
Nanofiber Nerve Cuffs to Inhibit Neuroma Formation
Nanofiber Nerve Cuff to Inhibit Neuroma FormationJHU Ref #: [C17593]Value Proposition:·        This device can be used to cap the end of a severed nerve to prevent unwanted nerve growth through a combination of physical and biochemical mechanisms.·        This device is more effective than existing nerve caps and cuffs, due to the inclusion of bioactive...
Published: 3/14/2025   |   Inventor(s): Hai-Quan Mao, Sami Tuffaha, Ahmet Hoke, Anson Zhou, Bruce Enzmann, Michael Lan, Erica Lee, Ruifa Mi, Russell Martin
Keywords(s):  
Category(s): Clinical and Disease Specializations > Neurology, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices
Robotic System for Remote Operation of Equipment in Infectious Environments
Unmet NeedDuring infectious disease outbreaks such as the recent coronavirus pandemic, patients often require life-sustaining medical equipment for care in the hospital setting. Infection control is both a priority and a challenge within the hospital setting due to increased infectious sources, susceptible patients, and chances for transmission (Center...
Published: 3/14/2025   |   Inventor(s): Russell Taylor, Axel Krieger, Peter Kazanzides, Balazs Vagvolgyi, Anton Deguet, Mikhail Khrenov
Keywords(s):  
Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Robotics
Biodegradable Nanofiber Conical Conduits for Targeted Muscle Reinnervation
Unmet NeedThere are 2 million amputees in the United States, with limb loss attributed to diabetes mellitus, vascular disease, trauma, and malignancy of bone and joints (Amputee Coalition, 2021 and Ziegler-Graham, et al., 2008).  Living with an amputation and the adoption of assistive devices like prosthetics can be challenging, with chronic pain especially...
Published: 3/14/2025   |   Inventor(s): Hai-Quan Mao, Sami Tuffaha, Ahmet Hoke, Michael Lan, Bruce Enzmann, Anson Zhou, Alison Wong, Erica Lee, Sai Pinni
Keywords(s):  
Category(s):  
Method of depositing nanotwinned nickel-molybdenum-tungsten alloys
Unmet NeedMetal MEMS devices would be very useful in extreme environments and especially at elevated temperatures, where potential future applications include: micro power generation, high frequency switches and sensors, and digital monitoring and control of residential and commercial components in what is often referred to as the “Internet of Things”....
Published: 3/13/2025   |   Inventor(s): Gi-Dong Sim, Jessica Krogstad, Timothy Weihs, Kevin Hemker, Gianna Valentino
Keywords(s): Industrial Manufacturing, Manufacturing Method, Novel Materials, Weaving
Category(s): Technology Classifications > Industrial Tech > Industrial Manufacturing, Technology Classifications > Industrial Tech > Materials, Technology Classifications > Industrial Tech, Technology Classifications > Engineering Tech > Industrial Manufacturing, Technology Classifications > Engineering Tech > Materials
Mechanistic insights reveal drug discovery target for lithium responders and non-responders
Value PropositionNew mouse model for mood switching behavior with viability for compound screeningDemonstrated that BK channels in excitatory neurons are involved in cellular pathology of patients by affecting Ca2+ kineticsApplication to both lithium responders and non-responders Unmet NeedBipolar disorder (BPD) has a lifetime prevalence of 4-5% in...
Published: 3/14/2025   |   Inventor(s): Akira Sawa, Rupali Srivastava, Koko Ishizuka
Keywords(s):  
Category(s): Clinical and Disease Specializations > Psychiatry > Bipolar Disorder, Clinical and Disease Specializations > Psychiatry > Mood Disorders, Clinical and Disease Specializations > Psychiatry > Suicidal Impulses, Technology Classifications > Research Tools > Animal Models
Directional Crystallization of Materials from a Solution
Value Proposition ·       Continuous Crystal Growth – the crystal is grown continuously out of a liquid solution, enabling the production of larger volume crystals compared to traditional batch processes·       Improved Crystal Quality – growth from a liquid solution prevents stress and defects caused by heterogeneous thermal contraction during cooling·       Higher...
Published: 3/14/2025   |   Inventor(s): Eli Zoghlin, Tyrel Mcqueen, James Edgar, Satya Kushwaha, Lucas Pressley
Keywords(s):  
Category(s): Technology Classifications > Engineering Tech > Electrical Engineering, Technology Classifications > Engineering Tech > Materials, Technology Classifications > Engineering Tech > Industrial Manufacturing, Technology Classifications > Industrial Tech > Materials
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