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Volumetric Interventional Tool Tracking and Patient Monitoring Method and Apparatus

Unmet NeedUltrasound-guided vascular access has also been shown to decrease cannulation time for emergent veno-arterial extracorporeal membrane oxygenation (VA-ECMO) cannulation in refractory cardiac arrest. Despite the increasingly widespread use of ultrasound for procedural guidance, reliable and accurate tracking of the device can be challenging...

Published: 3/14/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Laeben Lester, Keshuai Xu, Jintan Zhang

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Computers, Electronics & Software

Methods for in situ Detection of DNA Sequence Variation

Value Proposition· High-throughput· Assess genetic variants with simultaneous spatial analysis· Interrogate over 100 variants in a single assayUnmet Need· Next generation sequencing has led to an ever-proliferating dearth of genetic information. More recent progress in nucleoside tissue analysis has birthed the field of spatial...

Published: 3/14/2025 | Inventor(s): Reza Kalhor, Soichiro Asami

Keywords(s):

Category(s): Technology Classifications, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Bioinformatics, Technology Classifications > Research Tools > Imaging, Technology Classifications > Research Tools > Nucleic Acids

Apparatus and Method for modular ultrasound and photoacoustic imaging and interactive guidance using a position-tracked modular imaging framework

Value Proposition· Wearable ultrasound system that is adaptable to different patient physiologies and ages.· Allows for longitudinal and non-invasive monitoring of internal organs of critical care patients.· Applicable across a broad range of organ systems and disease indications.· Simulation-aided interactive guidance simplifies...

Published: 3/14/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Ananya Tandri

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Imaging

Non-contact Ultrasound Tomography Imaging System

Multifunctional 3D ultrasound imaging systemJHU Ref #: C17859Value Proposition:· Generation of high resolution 3D images for detection and diagnosis of diseases.· Overcomes previous required use of media (water) to image.· Media-less imaging ability allows for integration of other imaging techniques (MRI, PET, CT). Unmet Need· The...

Published: 3/14/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Hyunwoo Song, Yixuan Wu

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Nanofiber Nerve Cuffs to Inhibit Neuroma Formation

Nanofiber Nerve Cuff to Inhibit Neuroma FormationJHU Ref #: [C17593]Value Proposition:· This device can be used to cap the end of a severed nerve to prevent unwanted nerve growth through a combination of physical and biochemical mechanisms.· This device is more effective than existing nerve caps and cuffs, due to the inclusion of bioactive...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Sami Tuffaha, Ahmet Hoke, Anson Zhou, Bruce Enzmann, Michael Lan, Erica Lee, Ruifa Mi, Russell Martin

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices

Robotic System for Remote Operation of Equipment in Infectious Environments

Unmet NeedDuring infectious disease outbreaks such as the recent coronavirus pandemic, patients often require life-sustaining medical equipment for care in the hospital setting. Infection control is both a priority and a challenge within the hospital setting due to increased infectious sources, susceptible patients, and chances for transmission (Center...

Published: 3/14/2025 | Inventor(s): Russell Taylor, Axel Krieger, Peter Kazanzides, Balazs Vagvolgyi, Anton Deguet, Mikhail Khrenov

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Robotics

Biodegradable Nanofiber Conical Conduits for Targeted Muscle Reinnervation

Unmet NeedThere are 2 million amputees in the United States, with limb loss attributed to diabetes mellitus, vascular disease, trauma, and malignancy of bone and joints (Amputee Coalition, 2021 and Ziegler-Graham, et al., 2008). Living with an amputation and the adoption of assistive devices like prosthetics can be challenging, with chronic pain especially...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Sami Tuffaha, Ahmet Hoke, Michael Lan, Bruce Enzmann, Anson Zhou, Alison Wong, Erica Lee, Sai Pinni

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Category(s):

Method of depositing nanotwinned nickel-molybdenum-tungsten alloys

Unmet NeedMetal MEMS devices would be very useful in extreme environments and especially at elevated temperatures, where potential future applications include: micro power generation, high frequency switches and sensors, and digital monitoring and control of residential and commercial components in what is often referred to as the “Internet of Things”....

Published: 3/13/2025 | Inventor(s): Gi-Dong Sim, Jessica Krogstad, Timothy Weihs, Kevin Hemker, Gianna Valentino

Keywords(s): Industrial Manufacturing, Manufacturing Method, Novel Materials, Weaving

Category(s): Technology Classifications > Industrial Tech > Industrial Manufacturing, Technology Classifications > Industrial Tech > Materials, Technology Classifications > Industrial Tech, Technology Classifications > Engineering Tech > Industrial Manufacturing, Technology Classifications > Engineering Tech > Materials

Mechanistic insights reveal drug discovery target for lithium responders and non-responders

Value PropositionNew mouse model for mood switching behavior with viability for compound screeningDemonstrated that BK channels in excitatory neurons are involved in cellular pathology of patients by affecting Ca2+ kineticsApplication to both lithium responders and non-responders Unmet NeedBipolar disorder (BPD) has a lifetime prevalence of 4-5% in...

Published: 3/14/2025 | Inventor(s): Akira Sawa, Rupali Srivastava, Koko Ishizuka

Keywords(s):

Category(s): Clinical and Disease Specializations > Psychiatry > Bipolar Disorder, Clinical and Disease Specializations > Psychiatry > Mood Disorders, Clinical and Disease Specializations > Psychiatry > Suicidal Impulses, Technology Classifications > Research Tools > Animal Models

Directional Crystallization of Materials from a Solution

Value Proposition · Continuous Crystal Growth – the crystal is grown continuously out of a liquid solution, enabling the production of larger volume crystals compared to traditional batch processes· Improved Crystal Quality – growth from a liquid solution prevents stress and defects caused by heterogeneous thermal contraction during cooling· Higher...

Published: 3/14/2025 | Inventor(s): Eli Zoghlin, Tyrel Mcqueen, James Edgar, Satya Kushwaha, Lucas Pressley

Keywords(s):

Category(s): Technology Classifications > Engineering Tech > Electrical Engineering, Technology Classifications > Engineering Tech > Materials, Technology Classifications > Engineering Tech > Industrial Manufacturing, Technology Classifications > Industrial Tech > Materials

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