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Anastasis Biosensor CaspaseTracker rtTA – C15014 Unmet NeedAnastasis, Greek for "rising to life", is a newly discovered cell recovery phenomenon by which a cell undergoes reversal of apoptosis or programmed cell death. Research has shown that even cells that exhibit the hallmarks of late-stage cell death such as activation of executioner caspases...

Published: 3/13/2025 | Inventor(s): Ho Lam Tang, Ho Man Holly Tang

Keywords(s): Animal Imaging Tools, apoptosis, Biomarker, Clinical Diagnostics, Discovery/Research Tools, Imaging Agent, Imaging and Sensing Systems, In Vitro Diagnostics, In Vivo Medical Imaging, In Vivo Research Tool, Labels/Markers, Research Reagent

Category(s): Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics > Biomarkers

Creation of Murine Ovarian Cancer Cell Line Suitable for Non-Invasive Imaging

Trackable Murine Ovarian Cancer Cell LineJHU REF: [C12340]Invention novelty: This tangible material is a transgenic murine ovarian cancer cell line expressing luciferase for non-invasive monitoring of tumor load in a mouse bearing this cell line. Value Proposition: There is a need for cancer cell lines that can be monitored/detected non-invasively....

Published: 3/13/2025 | Inventor(s): T.c. Wu, Chien-Fu Hung

Keywords(s): Animal Imaging Tools, Assay, Basic Research Biomarker, Cancers, Cell Lines, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics (Old), In Vitro Research Tool, In Vivo Research Tool, Mouse Cell Lines, Ovarian Cancer

Category(s): Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology > Ovarian Cancer, Technology Classifications > Diagnostics > Diagnostic Imaging

Human Mesothelin Expressing ID8-Defb29 Vegf/Luc (ID8-Defb29 Vegf-Luc/Hmeso)

ABSTRACTCancer immunotherapy targeting mesothelin represents a potentially plausible approach for the control of ovarian cancer as most ovarian cancers express high levels of mesothelin. In the current study, JHU researchers created a mesothelin-positive luciferase-expressing ovarian cancer model, ID8-Defb29 Vegf /luc. ID8-Defb29 Vegf –luc was infected...

Published: 3/13/2025 | Inventor(s): T.c. Wu, Chien-Fu Hung

Keywords(s): Animal Imaging Tools, Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, In Vivo Research Tool, Ovarian Cancer

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology > Ovarian Cancer

4D Digital Mouse Whole Body (MOBY) Phantom

C04403: 4D Digital Mouse Whole Body (MOBY) PhantomNovelty: The 4D digital mouse whole body (MOBY) phantom is a realistic and flexible model of the mouse anatomy and cardiac and respiratory motions for use in molecular imaging research.Value Proposition: Currently, there is a lack of realistic computer generated phantoms modeling the mouse anatomy and...

Published: 3/13/2025 | Inventor(s): Benjamin Tsui, William Segars

Keywords(s): Animal Imaging Tools, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Discovery/Research Tools, In Vivo Research Tool, Physics

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Research Tools