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System and Method for Antimicrobial Drug Susceptibility Screening at the Bedside

Value Proposition· Faster, same‑day guidance for prescribing antibiotics: Rapid bedside screening platform that captures cultures and tests bacteria from clinical specimens (e.g., urine) to inform immediate antibiotics prescribing in doctors’ offices, urgent care, and outpatient clinics.· Useful for low‑volume infections: Because the system...

Published: 3/13/2026 | Inventor(s): Andrew Feldman, Hannah Gray, Jeffrey Lin, Charles Young

Keywords(s): Bacterial Infections, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Point of Care

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Precision Medicine Tools, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Applied Physics Laboratory > Applied Physics Laboratory

Biomimetic Platforms to Model Vascular Pathophysiology, Diagnostics, and Therapy

Value Proposition· Biomimetic platform of human pulmonary arterioles that enables researchers and clinicians to better understand pulmonary hypertension.· Precisely engineered, tunable, functional, and anatomically accurate biomimetic human pulmonary microvasculature supports quantitative analysis of endothelial and smooth muscle cell...

Published: 3/12/2026 | Inventor(s): Lewis Romer, David Gracias, Jayson Pagaduan, Anil Bhatta, Xing Chen, Qianru Jin

Keywords(s): Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Lung Disorders, Target-based Screening Tool

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Respiratory Diseases, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools, Technology Classifications > Diagnostics

Simple, blood-based multimarker diagnostic of pulmonary hypertension

Value Proposition· Blood-based diagnostic strategy to quickly confirm disease· Diagnostic potential is equivalent to current cumbersome clinical measurement· Less costly than standard diagnostic methodologies· Easily repurposed for monitoring progression and treatment responseUnmet Need· Pulmonary hypertension (PH) has an estimated...

Published: 3/13/2026 | Inventor(s): Allen Everett, Megan Griffiths, Jun Yang, Cedric Manlhiot

Keywords(s):

Category(s): Technology Classifications > Diagnostics

Genetic Barcode-Based Assay for Predicting Metastatic Risk Potential

Value Proposition:· Early detection of metastatic cancer: Accurately predicts metastatic cancer risk potential by detection of specific biological markers in patient tumors. · Applicability across multiple cancer types: Cancer biomarker detection technology that can be potentially applied to epithelial tumors including colon, breast, and...

Published: 3/13/2026 | Inventor(s): Reza Kalhor, Jesse Handler

Keywords(s):

Category(s): Technology Classifications > Diagnostics

Compositions and Biomarkers for Human Cancer and Methods of Use

Novel biomarkers for the detection and prognosis of several cancersJHU REF: C12506 Invention novelty: This invention has discovered high frequency mutations in the telomerase reverse transcriptase (TERT) promoter of certain cancers. Value Proposition: Early detection is usually critical for the successful treatment of cancer, therefore there is...

Published: 3/12/2026 | Inventor(s): Bert Vogelstein, Kenneth Kinzler, Nickolas Papadopoulos, Chetan Bettegowda, Yuchen Jiao, Darell Bigner, Hai Yan, Zachary Reitman, Patrick Killela

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Mechanism-of-action Biomarker, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > Prognostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Technology Classifications > Therapeutic Modalities

Hospital-to-Home-Health Transition Quality (H3TQ) Index

An express license for this technology is available via JHTV's online licensing portal.The Hospital-to-Home-Health Transition Quality (H3TQ) Index is a novel measure that identifies threats to patient safety in real time for older adults receiving skilled home healthcare (HH) services after hospital discharge. The H3TQ identifies organizational...

Published: 3/13/2026 | Inventor(s): Alicia Arbaje, Bruce Leff, Yea-Jen Hsu

Keywords(s):

Category(s): Clinical and Disease Specializations > Geriatrics, Technology Classifications > Diagnostics > Precision Medicine Tools, Technology Classifications > Diagnostics

Total Neuropathy Score - clinical (TNSc)

An express license for this technology is available via JHTV's online licensing portal.The Total Neuropathy Score - Clinical (TNSc) is a composite measure of peripheral neuropathy for use by physicians. Arising from studies of chemotherapy-induced peripheral neuropathy (CIPN), the Total Neuropathy Score (TNS) was originally developed and validated...

Published: 3/12/2026 | Inventor(s): Vinay Chaudhry, David Cornblath

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Measurement Tool

Category(s): Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Diagnostics

Total Neuropathy Score - Nurse

An express license for this technology is available via JHTV's online licensing portal.The Total Neuropathy Score - Nurse (TNSn) is a composite measure of peripheral neuropathy for use by trained non-physicians such as nurses or clinical research study coordinators.Arising from studies of chemotherapy-induced peripheral neuropathy (CIPN), the...

Published: 3/12/2026 | Inventor(s): Vinay Chaudhry, David Cornblath, Kathleen Griffith

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Screening Questionnaire

Category(s): Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics, Technology Classifications > Computers, Electronics & Software

Potential Energy Landscapes Reveal the Information-theoretic Nature of the Epigenome

Unmet NeedEpigenetics is the study of biochemical modifications carrying information independent of DNA sequence, which are heritable through cell division. To date, methylation landscapes have not yet been rigorously computed.Technology OverviewUsing principles from statistical physics and information theory, JHU inventors have derived epigenetic energy...

Published: 3/12/2026 | Inventor(s): Andrew Feinberg, John Goutsias, William Jenkinson, Elisabet Pujadas

Keywords(s): Assay, Clinical Diagnostics, In Vitro Diagnostics

Category(s): Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Technology Classifications > Research Tools

Methylated Markers for the Detection of Cervical Cancer

Unmet need:According to WHO, cervical cancer represents the fourth most common female cancer world-wide, with approximately 600,000 new cases as well as 300,000 deaths in 2020 alone (see WHO). Cervical cancer screening efforts aim to detect cancerous lesions in the cervix to enable earlier treatment. The main screening modalities include a Pap test...

Published: 3/13/2026 | Inventor(s): Saraswati Sukumar, MaryJo Fackler, Deyin Xing

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Cervical Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications, Technology Classifications > Diagnostics

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