Search Results - anirban+maitra

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Identification of RNF43 Mutations in Pancreatic Cysts

Unmet Need· One third of diagnoses for surgical resection of pancreatic cysts are incorrect, leading to unnecessary surgery, medical risk, and high costs (Hammel, 2002). The current standard of care for determining pancreatic cyst type is based solely on symptom progression and imaging criteria, and histopathological analysis is only available...

Published: 9/26/2024 | Inventor(s): Bert Vogelstein, Kenneth Kinzler, Nickolas Papadopoulos, Jian Wu, Anirban Maitra, Ralph Hruban, Marco Dal Molin

Keywords(s): Cancers, Cloning Reagents, Discovery/Research Tools, Disease Indication, Nucleotide, Pancreatic Cancer, Research Reagent, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Technology Classifications > Research Tools > Nucleic Acids, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology > Pancreatic Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers

Biocompatible "smart" nanogels as carriers for hydrophobic drugs

The present invention involves a biocompatible nanogel composition for the delivery of hydrophobic substances that are not readily soluble in organic solvents. These nanogels have been designed to contain hydrophobic cores which encapsulate the insoluble molecules, and a hydrophilic shell which allows long term systemic circulation. The nanogels constitute...

Published: 9/26/2024 | Inventor(s): Savita Bisht, Georg Feldmann, Anirban Maitra

Keywords(s): Drug Delivery Vehicle, Hydrogel, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities

SCID hprt-null, NOG hprt-null mice

Mouse models to cultivate cancer cellsJHU REF: [C12012 and C05132]Invention novelty: Propagation of human cancer cells in immunodeficient mice and isolation of these cells without contamination with mouse cells.Value Proposition: • These mouse lines may be used for various applications including: Cancer cell line isolation. These mice may...

Published: 9/26/2024 | Inventor(s): James Eshleman, Anirban Maitra

Keywords(s): Basic Research Biomarker, Cell Lines, Discovery/Research Tools, In Vitro Research Tool, In Vivo Research Tool, Mouse Cell Lines, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools

PXA1, PXA2, PXA3, PXA4, PXA5, PXA6

C04411: PXA1, PXA2, PXA3, PXA4, PXA5, PXA6 Technical Details: The invention consists of low-passage cell lines generated from primary pancreatic cancers established as nude-mice xenografts, and subsequently passaged in vitro.Looking for Partners: Due to their low-passage, these cell lines are more representative of the alterations in the pancreatic...

Published: 9/26/2024 | Inventor(s): Sunil Karhadkar, David Berman, Anirban Maitra, Philip Beachy

Keywords(s): Basic Research Biomarker, Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, In Vivo Research Tool, Mouse Cell Lines, Mouse Model, Mouse Model Xenograft, Pancreatic Cancer, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Oncology > Pancreatic Cancer