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Machine Learning System to Detect Streptococcus Pharyngitis (aka 'Strep Throat')

Unmet NeedThere are 7.8 million children diagnosed with pharyngitis each year, and another 4.8 M children with other associated complaints (respiratory symptoms or fever). These typically warrant a rapid strep test. The CDC estimates that there are 11,000 to 24,000 cases of strep throat each year in the United States, and that between 1,200 and 1,900...

Published: 3/14/2025 | Inventor(s): Therese Canares, Mathias Unberath, Roger Soberanis Mukul

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics > Diagnostic Imaging, Clinical and Disease Specializations > Ear, Nose & Throat

Greater Promoter Methylation and Somatic Mutation Analyses Reveal Alterations in PAX, NOTCH, and TP53 Pathways Associated with Poor Survival in Head and Neck Cancer

Novel Biomarkers for Predicting Head & Neck Cancer RiskC12502Invention Novelty: This invention provides DNA methylation-based biomarkers for predicting Head & Neck Cancer risk. Value Proposition: Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common cancer worldwide with more than 500,000 new cases and 300, 000 deaths each...

Published: 3/13/2025 | Inventor(s): Christina Michailidi, David Sidransky, Rafael Guerrero-Preston

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, Epigenetic, Head & Neck Cancer, Head and Neck Cancer, In Vitro Diagnostics, Methylation

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Head & Neck Cancer

Diffractive Tethered OCT Capsule Endoscope for Ultrahigh-resolution Imaging

Unmet Need:Optical coherence tomography (OCT) is a noninvasive, high-resolution optical imaging technology capable of real-time imaging of tissue microanatomy. OCT essentially functions as a form of “optical biopsy”, capable of assessing tissue microanatomy and function with a resolution similar to standard histology but without the need for tissue...

Published: 3/13/2025 | Inventor(s): Xingde Li

Keywords(s): Cancers, Disease Indication, Esophageal Cancer, Imaging and Sensing Systems, Imaging Probe/Transducer, In Vivo Medical Imaging, Integrated Imaging System

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Esophageal Cancer

Safety Feature for use with Robotically Manipulated Endoscopes and other Tools in Otolaryngology and Neurosurgery

Unmet NeedAs the medical world begins to embrace the implementation of robotics into their clinical applications, there is a just as important growing market towards their safety in their use, as patient safety is the number one priority. In the field of otology, there has been a significant increase in the use of operative endoscopes. The problem with...

Published: 3/14/2025 | Inventor(s): Russell Taylor, Francis Creighton

Keywords(s): CNS and Neurological Disorders, Disease Indication, Interventional and Surgical Systems, Robotic Surgical System Sensing, Robotic Surgical System Software, Surgical Navigation

Category(s): Technology Classifications > Medical Devices > Surgical, Technology Classifications > Computers, Electronics & Software > Robotics, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Neurology

A Device for Magnetic Stimulation of the Vestibular System

Unmet NeedVestibular disorders (dizziness, vertigo, imbalance) are ubiquitous problems in clinical medicine. They account for many millions of visits to physicians and therapists every year, and often produce prolonged physical and psychological disability leading to a loss of economic productivity and a high risk of falls and injuries. Like many other...

Published: 3/13/2025 | Inventor(s): Daniel Reich, Collin Broholm, David Zee, Dale Roberts, Michael Schubert, Jorge Otero-Millan, Bryan Ward

Keywords(s): Disease Indication, Ear and Hearing Disorders, Hearing Disorders, Other, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Ear, Nose & Throat > Hearing Disorders

A Device and Method to Treat Esophageal Disorders

Unmet needAn effective yet convenient method to treat esophageal disorders does not exist. For example, there is pressing need for non-invasive therapeutic options for patients with Barrett’s esophagus which progresses to low-grade dysplasia or high grade dysplasia. Technology OverviewJohns Hopkins researchers developed devices and methods to administer...

Published: 3/13/2025 | Inventor(s): Florin Selaru, Stephen Meltzer, George Coles, Honggang Cui

Keywords(s): Cancers, Disease Indication, Esophageal Cancer, Interventional and Surgical Systems

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat, Clinical and Disease Specializations > Oncology > Esophageal Cancer, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology

Endoscopic Abrasion Device

The present invention provides an endoscopic abrasion device and methods of use thereof. The device includes a catheter having an inflation balloon including one or more elements disposed on the balloon for abrasion of tissue when the balloon is rotated about the longitudinal axis of the catheter. The device may be used to treat and diagnose diseases...

Published: 3/13/2025 | Inventor(s): Mouen Khashab, Anthony Kalloo

Keywords(s): Cancers, Disease Indication, Esophageal Cancer, Interventional and Surgical Systems, Surgical Instruments

VESTIBULAR IMPLANT SYSTEM WITH LOW BATTERY ALERT

C12285: Vestibular Implant System with Low Battery AlertNovelty: This technology is a vestibular implant system with a low battery alert. The system includes an implantable stimulator which provides a signal to electrically stimulate target neural tissue for vestibular sensation.Value Proposition: One significant challenge for vestibular implant system...

Published: 3/13/2025 | Inventor(s): Roland Hessler, Andreas Jager, Martin Zimmerling, Carolyn Garnham, Gene Fridman, Charles Della Santina

Keywords(s): Disease Indication, Ear and Hearing Disorders, Electrical Stimulation Device, Implanted Device, Implants, Neuromodulator, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Ear, Nose & Throat

Implanted Tube and External Interface for Saline or Drug Delivery to the Paranasal Sinuses

C11873: Nasal Implant for Efficient Treatment of SinusitisNovelty: Implant improves drug delivery for the treatment of sinusitis.Value Proposition: In the United States, about 3 to 10 million people suffer from chronic sinusitis, caused by inflammation of the paranasal sinus tissue. Common treatment methods include saline irrigation and steroids, used...

Published: 3/13/2025 | Inventor(s): Marton Varady, Creighton Petty, Anastasia Borok, Lauren Kraiter, Andrew Lane

Keywords(s): Disease Indication, Drug Delivery Device, Implanted Device, Implants, Nose and Sinus Disorders, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Ear, Nose & Throat

Method and Apparatus for Cochlear Implant Surgery

C11232: Method and Apparatus for Cochlear Implant SurgeryNovelty: A method and configurable apparatus to the patient for cochlear implant surgery that provides feedback to the surgeon informing him or her of the distance by which the implant may be advanced before contact occurs.Value Proposition: Cochlear implant surgery can benefit patients with severe...

Published: 3/13/2025 | Inventor(s): Iulian Iordachita, John Niparko, Wade Chien, Russell Taylor

Keywords(s): Disease Indication, Ear and Hearing Disorders, Hearing Disorders, Implanted Device, Implants, Interventional and Surgical Systems, Surgical Instruments, Surgical Intervention Method, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat > Hearing Disorders, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Imaging

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