Search Results - clinical+and+disease+specializations+%3e+oncology+%3e+cervical+cancer

10 Results

Sort By:

MRI-Guided Active Injection Needle for Radiation-Oncology Brachytherapy

Unmet NeedEffective radiation treatment of tumors combines maximal radiation dose delivery to planned locations while mitigating radiation impacts on surrounding normal tissues. A delivery of radiation absorption materials (biocompatible gels) to create pockets of radiation dissipation has proven to be an effective method to mask unwanted effects. Most...

Published: 9/27/2024 | Inventor(s): Ehud Schmidt, Yue Chen, Anthony Gunderman, Henry Halperin, Akila Viswanathan, Ryan Baumgaertner, Marc Morcos

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

Annexin V-HPV E7 Fusion Protein for Cancer Treatment

Unmet needHuman papillomavirus (HPV) causes the majority of cases of cervical cancer, which affects approximately 500,000 women worldwide each year. Additionally, HPV has been associated with other cancers including penile, vaginal, vulvar, anal, and head and neck cancers. Currently, there are limited treatment options for patients with advanced cervical...

Published: 9/26/2024 | Inventor(s): T.c. Wu, Chien-Fu Hung, Tae Heung Kang

Keywords(s): Biomarker, Cancers, Cervical Cancer, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics (Old), Target, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations > Oncology > Cervical Cancer, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics > Biomarkers

Luciferase-expressing TC-1 Tumor Cells (TC-1/luc) Cell Line

ABSTRACTOne of the major limitations to ovarian cancer immunotherapy is the difficulty of generating ovarian cancer mouse models. Without suitable ovarian cancer models in immune intact mice, it will be difficult to test new therapies for ovarian cancers.Firefly luciferase-expressing TC-1 cells (TC-1-Luc) was generated by JHU researchers with retrovirus...

Published: 9/26/2024 | Inventor(s): T.c. Wu, Chien-Fu Hung

Keywords(s): Cancers, Cell Lines, Cervical Cancer, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Mouse Cell Lines, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools

Glioblastoma Biomarker for Improved Survival Prediction

TITLE: Glioblastoma Biomarker for Improved Survival PredictionCASE NUMBER: C13155UNMET NEEDGlioblastoma GBM), the most common primary brain tumor, has few available therapies providing significant improvement in survival. The median survival of patients after treatment is ~15 months, with only 3-5% surviving longer than 3 years. However, survival varies...

Published: 9/26/2024 | Inventor(s): Patrick Ha, Michael Lim, Chetan Bettegowda, Taeyoung Hwang, Chul-Kee Park, Dimitrios Mathios

Keywords(s): Biomarker, Brain Cancer, Breast Cancer, Cancers, Cervical Cancer, Clinical Diagnostics, Disease Indication, Glioma, In Vitro Diagnostics, Lung Cancer, Prognostic Biomarker

Vac-CRT/E7 and Vac-CRT

C10933: Vac-CRT/E7 and Vac-CRT Technical Details: The Vac-CRT/E7 vaccine can be employed to deliver chimeric CRT/E7 gene into the host cells in order to generate potent E7-specific CD8+ T cell immune responses and antitumor effects against E7- expressing tumors. Looking for Partners: Cervical cancer vaccine Publications: 1. Hsieh CJ, Kim...

Published: 9/26/2024 | Inventor(s): Chien-Fu Hung, T.c. Wu

Keywords(s): Cancers, Cervical Cancer, Disease Indication, Therapeutic Matter, Therapeutics

Unexpected Cross-neutralization of Cutaneous & Mucosal Papillomavirus Types with Anti-Sera to a Novel L2 Epitopes

C04603: Unexpected Cross-neutralization of Cutaneous & Mucosal Papillomavirus Types with Anti-Sera to a Novel Epitopes Technical Details: High risk Human Papillomavirus (HPV) infection is a common cause of cervical cancer. Researchers at JHU have found that vaccination with the N terminus of HPV16 and bovine papillomavirus 1 can induce cross...

Published: 9/26/2024 | Inventor(s): John Schiller, Douglas Lowy, Diane Pastrana, Ratish Gambhira, Richard Roden

Keywords(s): Biologics, Cancers, Cervical Cancer, Disease Indication, Human Papillomavirus (HPV), Infectious Diseases, Therapeutic Matter, Therapeutic Substance, Therapeutics, Vaccine

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases > Human Papillomavirus (HPV)

Probe for measuring Bioimpedance of the Human Uterine Cervix

C04241: Probe for measuring Bioimpedance of the Human Uterine Cervix Technical Details: There are various clinical conditions, both normal and abnormal, where significant remodeling of the proteins in the human uterine cervix occurs. For example, with increased secretion of decorin in late pregnancy and labor, collagen (the main component of the...

Published: 9/26/2024 | Inventor(s): Ashkon Shaahinfar, Kenny Hwee Seong Ching, Somponnat Sampattavanich, Yen Shi Hoe, Melanie Ruffner, Elbert Shangnung Hu, Edith Diament Allen

Keywords(s): Cancers, Cervical Cancer, Disease Indication, Electrical Impedance Probe, Imaging and Sensing Systems, Imaging Probe/Transducer, In Vivo Medical Imaging, Interventional and Surgical Systems, Probes, Surgical Instruments, Womens Health, Women's Health

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Women's Health, Technology Classifications > Computers, Electronics & Software > Sensors, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology > Cervical Cancer

Enhancement of DNA Vaccine Potency by Linking Marek's Disease Virus Type 1 VP22 to an Antigen

C03895: Enhancement of DNA Vaccine Potency by Linking Marek's Disease Virus Type 1 VP22 to an Antigen Technical Details: We have previously employed an spreading strategy using herpes simplex virus type 1 (HSV-1) VP22 protein to enhance DNA vaccine potency because DNA vaccines lack the intrinsic ability to amplify in cells. Recently, studies have demonstrated...

Published: 9/26/2024 | Inventor(s): Chien-Fu Hung, T.c. Wu

Keywords(s): Biologics, Cancers, Cervical Cancer, Disease Indication, Immunotherapy, Nucleic Acid, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Vaccine, Womens Health, Women's Health

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Oncology

Enhancement of Suicidal DNA Vaccine Potency by Linkage Mycobacterium Tuberculosis Heat Shock Protein 70 to an Antigen

C03797: Enhancement of Suicidal DNA Vaccine Potency by Linkage Mycobacterium Tuberculosis Heat Shock Protein 70 to an Antigen Technical Details: Naked DNA vaccines represent an attractive approach for generating antigen-specific immunity because of their stability and simplicity of delivery. There are particular concerns, however, such as potential...

Published: 9/26/2024 | Inventor(s): Chien-Fu Hung, T.c. Wu

Keywords(s): Biologics, Cancers, Cervical Cancer, Disease Indication, Immunotherapy, Nucleic Acid, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Vaccine

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Oncology

Superior Molecular Vaccine Linking the Translocation Domain of a Bacterial Toxin to an Antigen

UNMET NEED: Enhancement of antigen presentation through the MCH class I pathway to CD8+ T cells has been a primary focus of cancer immunotherapy. DNA vaccines have emerged as attractive approaches to generate CD8+ T cell responses in vaccinated humans. Yet, lack of potency and immunogenicity has limited their clinical utility to date. Disclosed herein...

Published: 9/26/2024 | Inventor(s): Chien-Fu Hung, T.c. Wu

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Oncology